Treatment of intractable gastrointestinal manifestations of chronic granulomatous disease with cyclosporine

Joel Rosh, Hope B. Tang, Lloyd Mayer, Gabriel Groisman, Sheeja K. Abraham, Alice Prince

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Gastrointestinal manifestations of chronic granulomatous disease of childhood include granulomatous inflammatory bowel disease. Severe colitis and perirectal disease developed in a 12-year-old boy with chronic granulomatous disease while he was receiving interferon gamma therapy. The boy had a deficiency of the 22 kd light chain of the cytochrome b heterodimer. After conventional medical therapy proved to be ineffective, a rapid clinical response was obtained to cyclosporine. (J PEDIATR 1995;126:143-5).

Original languageEnglish (US)
Pages (from-to)143-145
Number of pages3
JournalThe Journal of pediatrics
Volume126
Issue number1
DOIs
StatePublished - Jan 1 1995

Fingerprint

Chronic Granulomatous Disease
Cyclosporine
Cytochromes b
Colitis
Inflammatory Bowel Diseases
Interferon-gamma
Light
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Rosh, Joel ; Tang, Hope B. ; Mayer, Lloyd ; Groisman, Gabriel ; Abraham, Sheeja K. ; Prince, Alice. / Treatment of intractable gastrointestinal manifestations of chronic granulomatous disease with cyclosporine. In: The Journal of pediatrics. 1995 ; Vol. 126, No. 1. pp. 143-145.
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Treatment of intractable gastrointestinal manifestations of chronic granulomatous disease with cyclosporine. / Rosh, Joel; Tang, Hope B.; Mayer, Lloyd; Groisman, Gabriel; Abraham, Sheeja K.; Prince, Alice.

In: The Journal of pediatrics, Vol. 126, No. 1, 01.01.1995, p. 143-145.

Research output: Contribution to journalArticle

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