Transcatheter aortic valve implantation 10-year anniversary: Review of current evidence and clinical implications

Philippe Généreux, Stuart J. Head, David A. Wood, Susheel K. Kodali, Mathew R. Williams, Jean Michel Paradis, Marco Spaziano, A. Pieter Kappetein, John G. Webb, Alain Cribier, Martin B. Leon

Research output: Contribution to journalReview article

108 Citations (Scopus)

Abstract

Surgical aortic valve replacement (SAVR) is currently the standard of care to treat patients with severe symptomatic aortic stenosis (AS) and is generally accepted to alleviate symptoms and prolong survival. Based on the results of randomized trials, transcatheter aortic valve implantation (TAVI) is the new standard of care for patients with symptomatic AS who are deemed 'inoperable'. Debatably, TAVI is also an alternative to SAVR in selected patients who are at high risk but operable. As we approach 10 years of clinical experience with TAVI, with over 50 000 implantations in 40 countries, a review of the current literature and clinical outcomes with this rapidly evolving technology is appropriate.

Original languageEnglish (US)
Pages (from-to)2388-2400
Number of pages13
JournalEuropean Heart Journal
Volume33
Issue number19
DOIs
StatePublished - Oct 1 2012

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Anniversaries and Special Events
Aortic Valve Stenosis
Standard of Care
Aortic Valve
Surgical Instruments
Technology
Survival
Transcatheter Aortic Valve Replacement

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Généreux, Philippe ; Head, Stuart J. ; Wood, David A. ; Kodali, Susheel K. ; Williams, Mathew R. ; Paradis, Jean Michel ; Spaziano, Marco ; Kappetein, A. Pieter ; Webb, John G. ; Cribier, Alain ; Leon, Martin B. / Transcatheter aortic valve implantation 10-year anniversary : Review of current evidence and clinical implications. In: European Heart Journal. 2012 ; Vol. 33, No. 19. pp. 2388-2400.
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Généreux, P, Head, SJ, Wood, DA, Kodali, SK, Williams, MR, Paradis, JM, Spaziano, M, Kappetein, AP, Webb, JG, Cribier, A & Leon, MB 2012, 'Transcatheter aortic valve implantation 10-year anniversary: Review of current evidence and clinical implications', European Heart Journal, vol. 33, no. 19, pp. 2388-2400. https://doi.org/10.1093/eurheartj/ehs220

Transcatheter aortic valve implantation 10-year anniversary : Review of current evidence and clinical implications. / Généreux, Philippe; Head, Stuart J.; Wood, David A.; Kodali, Susheel K.; Williams, Mathew R.; Paradis, Jean Michel; Spaziano, Marco; Kappetein, A. Pieter; Webb, John G.; Cribier, Alain; Leon, Martin B.

In: European Heart Journal, Vol. 33, No. 19, 01.10.2012, p. 2388-2400.

Research output: Contribution to journalReview article

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AU - Généreux, Philippe

AU - Head, Stuart J.

AU - Wood, David A.

AU - Kodali, Susheel K.

AU - Williams, Mathew R.

AU - Paradis, Jean Michel

AU - Spaziano, Marco

AU - Kappetein, A. Pieter

AU - Webb, John G.

AU - Cribier, Alain

AU - Leon, Martin B.

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AB - Surgical aortic valve replacement (SAVR) is currently the standard of care to treat patients with severe symptomatic aortic stenosis (AS) and is generally accepted to alleviate symptoms and prolong survival. Based on the results of randomized trials, transcatheter aortic valve implantation (TAVI) is the new standard of care for patients with symptomatic AS who are deemed 'inoperable'. Debatably, TAVI is also an alternative to SAVR in selected patients who are at high risk but operable. As we approach 10 years of clinical experience with TAVI, with over 50 000 implantations in 40 countries, a review of the current literature and clinical outcomes with this rapidly evolving technology is appropriate.

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