The cell-sweep

A new cervical cytology sampling device

L. Tyau, E. Hernandez, L. Anderson, Paul Heller, P. Edmonds

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The Cell-Sweep, a new cervical cytology sampling device, was prospectively evaluated. From September 1, 1992, to October 31, 1992, 548 cervical cytology smears were prepared using the Cell-Sweep. They were compared to 524 cervical smears performed between January 1, 1993, and February 28, 1993, using the Cytobrush and Ayre spatula. One smear in the Cell-Sweep group and nine in the Cytobrush/Ayre spatula group were unsatisfactory for evaluation secondary to drying artifact (P < .01). Seven (1.2%) of the Cell-Sweep smears and 13 (2.4%) of the Cytobrush/Ayre spatula smears were inadequate due to obscuring of the epithelial cells by blood (P = .11). Of the smears obtained with the Cell-Sweep, 66 (12%) contained no endocervical component versus 42 (8%) of the smears obtained with the Cytobrush/Ayre spatula (P = .03). In the Cell- Sweep group there were 130 (23.7%) abnormal smears versus 110 (20.9%) in the Cytobrush/Ayre spatula group (P = .3). However, high grade squamous intraepithelial lesions (SILs) were identified in 10 (1.8%) smears obtained with the Cell-Sweep and in 2 (0.4%) obtained with the Cytobrush/Ayre spatula (P = .02). The Cell-Sweep produced a small proportion of unsatisfactory smears due to drying artifact or blood. Even though the proportion of smears lacking endocervical cells was statistically greater with the Cell-Sweep than with the Cytobrush/Ayre spatula, there was no difference in the rate of detection of atypical squamous cells and low grade SIL. The Cell-Sweep appears to detect an increased number of high grade SILs. This device deserves further study with histopathologic correlation.

Original languageEnglish (US)
Pages (from-to)899-902
Number of pages4
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume39
Issue number11
StatePublished - Dec 9 1994
Externally publishedYes

Fingerprint

Cell Biology
Equipment and Supplies
Vaginal Smears
Artifacts
Epithelial Cells

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Tyau, L. ; Hernandez, E. ; Anderson, L. ; Heller, Paul ; Edmonds, P. / The cell-sweep : A new cervical cytology sampling device. In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist. 1994 ; Vol. 39, No. 11. pp. 899-902.
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The cell-sweep : A new cervical cytology sampling device. / Tyau, L.; Hernandez, E.; Anderson, L.; Heller, Paul; Edmonds, P.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 39, No. 11, 09.12.1994, p. 899-902.

Research output: Contribution to journalArticle

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