Surgical treatment of Stages IB and IIA invasive carcinoma of the cervix by radical abdominal hysterectomy

Sanford Sall, Albert A. Pineda, Antonio Calanog, Paul Heller, Harvey Greenberg

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

From 1963 to 1977, 349 radical abdominal hysterectomies with bilateral pelvic lymphadenectomy were performed for Stage IB (331 patients) and Stage IIA (18 patients) cervical cancer at the New York Medical College, with no operative deaths. Definitive diagnosis was obtained from the biopsy specimen in 281 patients. Twenty-nine patients were pregnant when the diagnosis was established. The average operating time was 4 hours and 48 minutes with an average blood loss of 900 ml. Eleven fistulas were noted: ureterovaginal, 7; vesicovaginal, 3; rectovaginal, 1. Since 1972, there have been no fistulas in 130 radical hysterectomies. Metastatic carcinoma to the regional lymph nodes was discovered in 27 patients for an incidence of 7.7%. Postoperative total pelvic external irradiation was utilized in 40 patients (27 with positive nodes, 10 with microscopic carcinoma in vascular channels, and an additional three patients with an inadequate vaginal extirpation margin). A total of 62% of those patients with poor prognostic criteria receiving postoperative irradiation are alive and well. Two hundred nineteen patients have been followed up for at least 5 years and the survival rate was 90%. Our data support the view that radical abdominal hysterectomy with bilateral pelvic lymphadenectomy is the treatment of choice for patients with Stages IB and IIA cervical cancer in the nonpregnant state, unless there are major medical contraindications.

Original languageEnglish (US)
Pages (from-to)442-446
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume135
Issue number4
DOIs
StatePublished - Oct 15 1979
Externally publishedYes

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Hysterectomy
Cervix Uteri
Carcinoma
Therapeutics
Lymph Node Excision
Uterine Cervical Neoplasms
Fistula
Blood Vessels
Survival Rate
Lymph Nodes
Biopsy
Incidence

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Sall, Sanford ; Pineda, Albert A. ; Calanog, Antonio ; Heller, Paul ; Greenberg, Harvey. / Surgical treatment of Stages IB and IIA invasive carcinoma of the cervix by radical abdominal hysterectomy. In: American Journal of Obstetrics and Gynecology. 1979 ; Vol. 135, No. 4. pp. 442-446.
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abstract = "From 1963 to 1977, 349 radical abdominal hysterectomies with bilateral pelvic lymphadenectomy were performed for Stage IB (331 patients) and Stage IIA (18 patients) cervical cancer at the New York Medical College, with no operative deaths. Definitive diagnosis was obtained from the biopsy specimen in 281 patients. Twenty-nine patients were pregnant when the diagnosis was established. The average operating time was 4 hours and 48 minutes with an average blood loss of 900 ml. Eleven fistulas were noted: ureterovaginal, 7; vesicovaginal, 3; rectovaginal, 1. Since 1972, there have been no fistulas in 130 radical hysterectomies. Metastatic carcinoma to the regional lymph nodes was discovered in 27 patients for an incidence of 7.7{\%}. Postoperative total pelvic external irradiation was utilized in 40 patients (27 with positive nodes, 10 with microscopic carcinoma in vascular channels, and an additional three patients with an inadequate vaginal extirpation margin). A total of 62{\%} of those patients with poor prognostic criteria receiving postoperative irradiation are alive and well. Two hundred nineteen patients have been followed up for at least 5 years and the survival rate was 90{\%}. Our data support the view that radical abdominal hysterectomy with bilateral pelvic lymphadenectomy is the treatment of choice for patients with Stages IB and IIA cervical cancer in the nonpregnant state, unless there are major medical contraindications.",
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Surgical treatment of Stages IB and IIA invasive carcinoma of the cervix by radical abdominal hysterectomy. / Sall, Sanford; Pineda, Albert A.; Calanog, Antonio; Heller, Paul; Greenberg, Harvey.

In: American Journal of Obstetrics and Gynecology, Vol. 135, No. 4, 15.10.1979, p. 442-446.

Research output: Contribution to journalArticle

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