Salivary mucoepidermoid carcinoma revisited

Andrés Coca-Pelaz, Juan P. Rodrigo, Asterios Triantafyllou, Jennifer L. Hunt, Alessandra Rinaldo, Primož Strojan, Missak Haigentz, William M. Mendenhall, Robert P. Takes, Vincent Vander Poorten, Alfio Ferlito

Research output: Contribution to journalReview article

41 Citations (Scopus)

Abstract

Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.

Original languageEnglish (US)
Pages (from-to)799-819
Number of pages21
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume272
Issue number4
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

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Mucoepidermoid Carcinoma
Cytophotometry
Salivary Glands
Uncertainty
Electron Microscopy
Neck
Immunohistochemistry
Head
Genes
Therapeutics

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Coca-Pelaz, A., Rodrigo, J. P., Triantafyllou, A., Hunt, J. L., Rinaldo, A., Strojan, P., ... Ferlito, A. (2015). Salivary mucoepidermoid carcinoma revisited. European Archives of Oto-Rhino-Laryngology, 272(4), 799-819. https://doi.org/10.1007/s00405-014-3053-z
Coca-Pelaz, Andrés ; Rodrigo, Juan P. ; Triantafyllou, Asterios ; Hunt, Jennifer L. ; Rinaldo, Alessandra ; Strojan, Primož ; Haigentz, Missak ; Mendenhall, William M. ; Takes, Robert P. ; Vander Poorten, Vincent ; Ferlito, Alfio. / Salivary mucoepidermoid carcinoma revisited. In: European Archives of Oto-Rhino-Laryngology. 2015 ; Vol. 272, No. 4. pp. 799-819.
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Coca-Pelaz, A, Rodrigo, JP, Triantafyllou, A, Hunt, JL, Rinaldo, A, Strojan, P, Haigentz, M, Mendenhall, WM, Takes, RP, Vander Poorten, V & Ferlito, A 2015, 'Salivary mucoepidermoid carcinoma revisited', European Archives of Oto-Rhino-Laryngology, vol. 272, no. 4, pp. 799-819. https://doi.org/10.1007/s00405-014-3053-z

Salivary mucoepidermoid carcinoma revisited. / Coca-Pelaz, Andrés; Rodrigo, Juan P.; Triantafyllou, Asterios; Hunt, Jennifer L.; Rinaldo, Alessandra; Strojan, Primož; Haigentz, Missak; Mendenhall, William M.; Takes, Robert P.; Vander Poorten, Vincent; Ferlito, Alfio.

In: European Archives of Oto-Rhino-Laryngology, Vol. 272, No. 4, 01.01.2015, p. 799-819.

Research output: Contribution to journalReview article

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T1 - Salivary mucoepidermoid carcinoma revisited

AU - Coca-Pelaz, Andrés

AU - Rodrigo, Juan P.

AU - Triantafyllou, Asterios

AU - Hunt, Jennifer L.

AU - Rinaldo, Alessandra

AU - Strojan, Primož

AU - Haigentz, Missak

AU - Mendenhall, William M.

AU - Takes, Robert P.

AU - Vander Poorten, Vincent

AU - Ferlito, Alfio

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AB - Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.

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Coca-Pelaz A, Rodrigo JP, Triantafyllou A, Hunt JL, Rinaldo A, Strojan P et al. Salivary mucoepidermoid carcinoma revisited. European Archives of Oto-Rhino-Laryngology. 2015 Jan 1;272(4):799-819. https://doi.org/10.1007/s00405-014-3053-z