Roles of substance P in gastrointestinal functions and neuroimmune interactions

Janek Vilisaar, Razvan Arsenescu

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Substance P (SP), a member of the tachykinin (TK) peptide family, is ubiquitously expressed from invertebrates to mammals with a role in different organ systems and a number of functions also in the gastrointestinal (GI) tract. In the current chapter, the roles of SP and other TKs in the GI tract with wider implications and its role in intersystem communication are emphasized. Roles for SP and different neurokinin receptors in the enteric nervous system and neuroimmune modulation are covered. In disease, SP roles in autoimmune and other inflammatory and infectious conditions are summarized.

Original languageEnglish (US)
Title of host publicationNeuro-Immuno-Gastroenterology
PublisherSpringer International Publishing
Pages53-73
Number of pages21
ISBN (Electronic)9783319286099
ISBN (Print)9783319286075
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Fingerprint

Substance P
Gastrointestinal Tract
Enteric Nervous System
Tachykinins
Invertebrates
Mammals
Communication
Peptides

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Vilisaar, J., & Arsenescu, R. (2016). Roles of substance P in gastrointestinal functions and neuroimmune interactions. In Neuro-Immuno-Gastroenterology (pp. 53-73). Springer International Publishing. https://doi.org/10.1007/978-3-319-28609-9_4
Vilisaar, Janek ; Arsenescu, Razvan. / Roles of substance P in gastrointestinal functions and neuroimmune interactions. Neuro-Immuno-Gastroenterology. Springer International Publishing, 2016. pp. 53-73
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Vilisaar, J & Arsenescu, R 2016, Roles of substance P in gastrointestinal functions and neuroimmune interactions. in Neuro-Immuno-Gastroenterology. Springer International Publishing, pp. 53-73. https://doi.org/10.1007/978-3-319-28609-9_4

Roles of substance P in gastrointestinal functions and neuroimmune interactions. / Vilisaar, Janek; Arsenescu, Razvan.

Neuro-Immuno-Gastroenterology. Springer International Publishing, 2016. p. 53-73.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Vilisaar J, Arsenescu R. Roles of substance P in gastrointestinal functions and neuroimmune interactions. In Neuro-Immuno-Gastroenterology. Springer International Publishing. 2016. p. 53-73 https://doi.org/10.1007/978-3-319-28609-9_4