Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome

P. Singer, Michael Rothkopf, V. Kvetan, O. Kirvela, J. Gaare, J. Askanazi

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The gastrointestinal tract is a major target of the human immunodeficiency virus. Many AIDS patients have weight loss and/or diarrhea. Parenteral nutrition can be used to treat malnutrition associated with malabsorption. We reviewed retrospectively the clinical course of 22 patients with AIDS and weight loss greater than 10% who received home parenteral nutrition (HPN) for 56.2 patient-months. Mean weight loss was 21.4%, mean duration of HPN 2.55 months, mean age 37.4 years. Fifteen patients gained weight, six stabilized and two continued to lose weight. Nine patients returned to previous activity. Five died. The rates of catheter-related sepsis, complications, and metabolic disturbances were 0.12, 0.25, and 0.12/100 catheter days, respectively, results identical to those reported in other patient populations where HPN is commonly applied. We found that HPN induced weight gain and clinical improvement in most patients without higher risks of sepsis than in patients with malignancies.

Original languageEnglish (US)
Pages (from-to)75-79
Number of pages5
JournalJournal of Parenteral and Enteral Nutrition
Volume15
Issue number1
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

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Home Parenteral Nutrition
Acquired Immunodeficiency Syndrome
Weight Loss
Sepsis
Catheters
Weights and Measures
Parenteral Nutrition
Malnutrition
Weight Gain
Gastrointestinal Tract
Diarrhea
HIV

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Singer, P. ; Rothkopf, Michael ; Kvetan, V. ; Kirvela, O. ; Gaare, J. ; Askanazi, J. / Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome. In: Journal of Parenteral and Enteral Nutrition. 1991 ; Vol. 15, No. 1. pp. 75-79.
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Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome. / Singer, P.; Rothkopf, Michael; Kvetan, V.; Kirvela, O.; Gaare, J.; Askanazi, J.

In: Journal of Parenteral and Enteral Nutrition, Vol. 15, No. 1, 01.01.1991, p. 75-79.

Research output: Contribution to journalArticle

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