Abstract
Paravalvular leak (PVL) is a frequent complication of transcatheter aortic valve replacement (TAVR) and is seen at a much higher rate after TAVR than after conventional surgical aortic valve replacement. Recent reports indicating that PVL may be correlated with increased late mortality have raised concerns. However, the heterogeneity of Methods: for assessing and quantifying PVL, and lack of consistency in the timing of such assessments, is a hindrance to understanding its true prevalence, severity, and effect. This literature review is an effort to consolidate current knowledge in this area to better understand the prevalence, progression, and impact of post-TAVR PVL and to help direct future efforts regarding the assessment, prevention, and treatment of this troublesome complication.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1125-1136 |
| Number of pages | 12 |
| Journal | Journal of the American College of Cardiology |
| Volume | 61 |
| Issue number | 11 |
| DOIs | |
| State | Published - Mar 19 2013 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
Cite this
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Paravalvular leak after transcatheter aortic valve replacement : The new achilles' heel? A comprehensive review of the literature. / Généreux, Philippe; Head, Stuart J.; Hahn, Rebecca; Daneault, Benoit; Kodali, Susheel; Williams, Mathew R.; Van Mieghem, Nicolas M.; Alu, Maria C.; Serruys, Patrick W.; Kappetein, A. Pieter; Leon, Martin B.
In: Journal of the American College of Cardiology, Vol. 61, No. 11, 19.03.2013, p. 1125-1136.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Paravalvular leak after transcatheter aortic valve replacement
T2 - The new achilles' heel? A comprehensive review of the literature
AU - Généreux, Philippe
AU - Head, Stuart J.
AU - Hahn, Rebecca
AU - Daneault, Benoit
AU - Kodali, Susheel
AU - Williams, Mathew R.
AU - Van Mieghem, Nicolas M.
AU - Alu, Maria C.
AU - Serruys, Patrick W.
AU - Kappetein, A. Pieter
AU - Leon, Martin B.
PY - 2013/3/19
Y1 - 2013/3/19
N2 - Paravalvular leak (PVL) is a frequent complication of transcatheter aortic valve replacement (TAVR) and is seen at a much higher rate after TAVR than after conventional surgical aortic valve replacement. Recent reports indicating that PVL may be correlated with increased late mortality have raised concerns. However, the heterogeneity of Methods: for assessing and quantifying PVL, and lack of consistency in the timing of such assessments, is a hindrance to understanding its true prevalence, severity, and effect. This literature review is an effort to consolidate current knowledge in this area to better understand the prevalence, progression, and impact of post-TAVR PVL and to help direct future efforts regarding the assessment, prevention, and treatment of this troublesome complication.
AB - Paravalvular leak (PVL) is a frequent complication of transcatheter aortic valve replacement (TAVR) and is seen at a much higher rate after TAVR than after conventional surgical aortic valve replacement. Recent reports indicating that PVL may be correlated with increased late mortality have raised concerns. However, the heterogeneity of Methods: for assessing and quantifying PVL, and lack of consistency in the timing of such assessments, is a hindrance to understanding its true prevalence, severity, and effect. This literature review is an effort to consolidate current knowledge in this area to better understand the prevalence, progression, and impact of post-TAVR PVL and to help direct future efforts regarding the assessment, prevention, and treatment of this troublesome complication.
UR - http://www.scopus.com/inward/record.url?scp=84877102732&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84877102732&partnerID=8YFLogxK
U2 - 10.1016/j.jacc.2012.08.1039
DO - 10.1016/j.jacc.2012.08.1039
M3 - Review article
C2 - 23375925
AN - SCOPUS:84877102732
VL - 61
SP - 1125
EP - 1136
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
SN - 0735-1097
IS - 11
ER -