Novel Crossing System for the Recanalization of Complex Chronic Total Occlusions: Ex vivo Proof of Concept of the SoundBite Crossing System

Simon Bérubé, Andrew Benko, Marc Antoine Despatis, Louis Philippe Riel, Marianne Brodmann, Eric Therasse, Martin Brouillette, Jihad A. Mustapha, Philippe Genereux

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Chronic total occlusion (CTO) lesions are frequent in patients with peripheral and coronary artery disease, and associated with a higher risk of adverse events, including mortality, decreased quality of life, and increased health-care costs. Percutaneous intervention of CTO lesions has been associated with a lower procedural success rate, and current dedicated CTO devices may be of limited use for the non-CTO expert, and associated with increased intraprocedural complication rates. The SoundBite Crossing System (SoundBite Medical Solutions, Inc) is a newly developed device using shockwaves (short-duration, high-Amplitude pressure pulses) to facilitate penetration of the proximal cap and crossing of the occlusion. The current report describes the first use of the SoundBite Crossing System in the recanalization of human ex vivo occluded arteries below the knee during a simulated procedure performed under fluoroscopy. Microcomputed tomography and histologic evaluation of the occluded and recanalized segment are provided to support therapeutic mechanism.

Original languageEnglish (US)
Pages (from-to)E47-E50
JournalJournal of Invasive Cardiology
Volume29
Issue number4
StatePublished - Apr 1 2017
Externally publishedYes

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X-Ray Microtomography
Equipment and Supplies
Peripheral Arterial Disease
Fluoroscopy
Health Care Costs
Coronary Artery Disease
Knee
Arteries
Quality of Life
Blood Pressure
Mortality
Therapeutics

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Bérubé, Simon ; Benko, Andrew ; Despatis, Marc Antoine ; Riel, Louis Philippe ; Brodmann, Marianne ; Therasse, Eric ; Brouillette, Martin ; Mustapha, Jihad A. ; Genereux, Philippe. / Novel Crossing System for the Recanalization of Complex Chronic Total Occlusions : Ex vivo Proof of Concept of the SoundBite Crossing System. In: Journal of Invasive Cardiology. 2017 ; Vol. 29, No. 4. pp. E47-E50.
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Bérubé, S, Benko, A, Despatis, MA, Riel, LP, Brodmann, M, Therasse, E, Brouillette, M, Mustapha, JA & Genereux, P 2017, 'Novel Crossing System for the Recanalization of Complex Chronic Total Occlusions: Ex vivo Proof of Concept of the SoundBite Crossing System', Journal of Invasive Cardiology, vol. 29, no. 4, pp. E47-E50.

Novel Crossing System for the Recanalization of Complex Chronic Total Occlusions : Ex vivo Proof of Concept of the SoundBite Crossing System. / Bérubé, Simon; Benko, Andrew; Despatis, Marc Antoine; Riel, Louis Philippe; Brodmann, Marianne; Therasse, Eric; Brouillette, Martin; Mustapha, Jihad A.; Genereux, Philippe.

In: Journal of Invasive Cardiology, Vol. 29, No. 4, 01.04.2017, p. E47-E50.

Research output: Contribution to journalArticle

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AU - Benko, Andrew

AU - Despatis, Marc Antoine

AU - Riel, Louis Philippe

AU - Brodmann, Marianne

AU - Therasse, Eric

AU - Brouillette, Martin

AU - Mustapha, Jihad A.

AU - Genereux, Philippe

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