Neuroaxonal Dystrophy and Down's Syndrome

Report of a Case

John Halperin, Dennis M.D. Landis, Ira T. Lott, Laura Ment

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An infant girl with Down's syndrome at birth manifested only mild developmental delay during the first 18 months of life. During the next six months, however, progressive deterioration in cognitive and motor function emerged. Thorough clinical and biochemical evaluation failed to determine the origin of the sensorimotor neuropathy, visual dysfunction, abnormal eye movements, and intellectual decline that developed. A sural nerve biopsy specimen revealed structures typical of neuroaxonal dystrophy.

Original languageEnglish (US)
Pages (from-to)587-591
Number of pages5
JournalArchives of Neurology
Volume39
Issue number9
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

Fingerprint

Neuroaxonal Dystrophies
Sural Nerve
Dyskinesias
Eye Movements
Down Syndrome
Cognition
Parturition
Biopsy
Evaluation
Nerve
Sensorimotor
Deterioration

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

Halperin, John ; Landis, Dennis M.D. ; Lott, Ira T. ; Ment, Laura. / Neuroaxonal Dystrophy and Down's Syndrome : Report of a Case. In: Archives of Neurology. 1982 ; Vol. 39, No. 9. pp. 587-591.
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Neuroaxonal Dystrophy and Down's Syndrome : Report of a Case. / Halperin, John; Landis, Dennis M.D.; Lott, Ira T.; Ment, Laura.

In: Archives of Neurology, Vol. 39, No. 9, 01.01.1982, p. 587-591.

Research output: Contribution to journalArticle

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