Nervous System Lyme Disease

Research output: Contribution to journalReview article

72 Citations (Scopus)

Abstract

Lyme disease affects the nervous system in about 10% to 15% of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculitis, radicular pain involving a limb or trunk dermatome. Treatment of neuroborreliosis is usually straightforward; oral antibiotics may suffice in many patients. In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit.

Original languageEnglish (US)
Pages (from-to)261-274
Number of pages14
JournalInfectious Disease Clinics of North America
Volume22
Issue number2
DOIs
StatePublished - Jun 1 2008
Externally publishedYes

Fingerprint

Lyme Neuroborreliosis
Cranial Nerve Diseases
Radiculopathy
Facial Paralysis
Facial Nerve
Meningitis
Therapeutics
Extremities
Anti-Bacterial Agents
Pain

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

@article{b5d016b2222b49b89bb9bbd582ae7140,
title = "Nervous System Lyme Disease",
abstract = "Lyme disease affects the nervous system in about 10{\%} to 15{\%} of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculitis, radicular pain involving a limb or trunk dermatome. Treatment of neuroborreliosis is usually straightforward; oral antibiotics may suffice in many patients. In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit.",
author = "John Halperin",
year = "2008",
month = "6",
day = "1",
doi = "10.1016/j.idc.2007.12.009",
language = "English (US)",
volume = "22",
pages = "261--274",
journal = "Infectious Disease Clinics of North America",
issn = "0891-5520",
publisher = "W.B. Saunders Ltd",
number = "2",

}

Nervous System Lyme Disease. / Halperin, John.

In: Infectious Disease Clinics of North America, Vol. 22, No. 2, 01.06.2008, p. 261-274.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Nervous System Lyme Disease

AU - Halperin, John

PY - 2008/6/1

Y1 - 2008/6/1

N2 - Lyme disease affects the nervous system in about 10% to 15% of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculitis, radicular pain involving a limb or trunk dermatome. Treatment of neuroborreliosis is usually straightforward; oral antibiotics may suffice in many patients. In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit.

AB - Lyme disease affects the nervous system in about 10% to 15% of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculitis, radicular pain involving a limb or trunk dermatome. Treatment of neuroborreliosis is usually straightforward; oral antibiotics may suffice in many patients. In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit.

UR - http://www.scopus.com/inward/record.url?scp=42949092265&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=42949092265&partnerID=8YFLogxK

U2 - 10.1016/j.idc.2007.12.009

DO - 10.1016/j.idc.2007.12.009

M3 - Review article

VL - 22

SP - 261

EP - 274

JO - Infectious Disease Clinics of North America

JF - Infectious Disease Clinics of North America

SN - 0891-5520

IS - 2

ER -