Nervous System Abnormalities and Legionnaire's Disease

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Although patients with Legionnaire's disease frequently develop alterations of consciousness, this is no more frequent than in patients hospitalized with other, equally severe forms of bacterial pneumonia. Legionella meningitis occurs rarely, if ever. Patients with Legionnaire's are susceptible to critical illness polyneuropathy/myopathy, as are other critically ill patients. Legionnaire's patients may develop MRI hyperdensities in the splenium of the corpus callosum, as may other patients with severe infections. Patients with Legionnaire's may be at increased risk of, and rarely develop, immune-mediated multifocal brain (acute disseminated encephalomyelitis) or peripheral nerve disease (Guillain-Barré syndrome).

Original languageEnglish (US)
Pages (from-to)55-68
Number of pages14
JournalInfectious Disease Clinics of North America
Volume31
Issue number1
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

Fingerprint

Nervous System Malformations
Legionnaires' Disease
Nervous System Diseases
Acute Disseminated Encephalomyelitis
Bacterial Pneumonia
Legionella
Polyneuropathies
Corpus Callosum
Peripheral Nervous System Diseases
Muscular Diseases
Consciousness
Meningitis
Critical Illness
Brain
Infection

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

@article{34fc187626364e009a449ad37ab54269,
title = "Nervous System Abnormalities and Legionnaire's Disease",
abstract = "Although patients with Legionnaire's disease frequently develop alterations of consciousness, this is no more frequent than in patients hospitalized with other, equally severe forms of bacterial pneumonia. Legionella meningitis occurs rarely, if ever. Patients with Legionnaire's are susceptible to critical illness polyneuropathy/myopathy, as are other critically ill patients. Legionnaire's patients may develop MRI hyperdensities in the splenium of the corpus callosum, as may other patients with severe infections. Patients with Legionnaire's may be at increased risk of, and rarely develop, immune-mediated multifocal brain (acute disseminated encephalomyelitis) or peripheral nerve disease (Guillain-Barr{\'e} syndrome).",
author = "John Halperin",
year = "2017",
month = "3",
day = "1",
doi = "10.1016/j.idc.2016.10.005",
language = "English (US)",
volume = "31",
pages = "55--68",
journal = "Infectious Disease Clinics of North America",
issn = "0891-5520",
publisher = "W.B. Saunders Ltd",
number = "1",

}

Nervous System Abnormalities and Legionnaire's Disease. / Halperin, John.

In: Infectious Disease Clinics of North America, Vol. 31, No. 1, 01.03.2017, p. 55-68.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Nervous System Abnormalities and Legionnaire's Disease

AU - Halperin, John

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Although patients with Legionnaire's disease frequently develop alterations of consciousness, this is no more frequent than in patients hospitalized with other, equally severe forms of bacterial pneumonia. Legionella meningitis occurs rarely, if ever. Patients with Legionnaire's are susceptible to critical illness polyneuropathy/myopathy, as are other critically ill patients. Legionnaire's patients may develop MRI hyperdensities in the splenium of the corpus callosum, as may other patients with severe infections. Patients with Legionnaire's may be at increased risk of, and rarely develop, immune-mediated multifocal brain (acute disseminated encephalomyelitis) or peripheral nerve disease (Guillain-Barré syndrome).

AB - Although patients with Legionnaire's disease frequently develop alterations of consciousness, this is no more frequent than in patients hospitalized with other, equally severe forms of bacterial pneumonia. Legionella meningitis occurs rarely, if ever. Patients with Legionnaire's are susceptible to critical illness polyneuropathy/myopathy, as are other critically ill patients. Legionnaire's patients may develop MRI hyperdensities in the splenium of the corpus callosum, as may other patients with severe infections. Patients with Legionnaire's may be at increased risk of, and rarely develop, immune-mediated multifocal brain (acute disseminated encephalomyelitis) or peripheral nerve disease (Guillain-Barré syndrome).

UR - http://www.scopus.com/inward/record.url?scp=85008867823&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85008867823&partnerID=8YFLogxK

U2 - 10.1016/j.idc.2016.10.005

DO - 10.1016/j.idc.2016.10.005

M3 - Review article

C2 - 27979685

AN - SCOPUS:85008867823

VL - 31

SP - 55

EP - 68

JO - Infectious Disease Clinics of North America

JF - Infectious Disease Clinics of North America

SN - 0891-5520

IS - 1

ER -