Malignant mesothelioma in young adults

Michael Kane, A. Philippe Chahinian, James F. Holland

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Ten cases of malignant mesothelioma presenting in patients 40 years old or younger at diagnosis were reviewed. Seven cases had a documented history of asbestos exposure of which five were household exposures. The median age at first exposure to asbestos was 10 years and the median duration of exposure was 120 months. The median latency period (time between initial asbestos exposure and diagnosis of malignant mesothelioma) was 19 years. The median interval from initial symptoms to definitive diagnosis was 5.5 months. The case history of each patient is presented. A significant delay in diagnosis in this age group compared with an ageunrestricted series is noted. The significance of nonoccupational exposure to asbestos is emphasized as a probable causative factor in the development of malignant mesothelioma. In addition, a possible genetic predisposition is briefly discussed.

Original languageEnglish (US)
Pages (from-to)1449-1455
Number of pages7
JournalCancer
Volume65
Issue number6
DOIs
StatePublished - Jan 1 1990

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Asbestos
Young Adult
Genetic Predisposition to Disease
Age Groups
Malignant Mesothelioma

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Kane, Michael ; Chahinian, A. Philippe ; Holland, James F. / Malignant mesothelioma in young adults. In: Cancer. 1990 ; Vol. 65, No. 6. pp. 1449-1455.
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Malignant mesothelioma in young adults. / Kane, Michael; Chahinian, A. Philippe; Holland, James F.

In: Cancer, Vol. 65, No. 6, 01.01.1990, p. 1449-1455.

Research output: Contribution to journalArticle

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