Lyme neuroborreliosis

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Lyme disease, the multisystem infectious disease caused by the tick-borne spirochaete Borrelia burgdorferi, has been well characterised over the past quarter century. When it is disseminated, multiple organ systems can be involved, with prominent involvement of joints, heart and both the peripheral and central nervous systems. Diagnosis is based on clinical presentation, with serological confirmation of exposure, using a combination of ELISA and Western blot techniques. When central nervous system involvement is suspected, examination of spinal fluid is invaluable. Even when infection has disseminated, and has been present for extended periods of time, response to conventional antibacterial therapy is excellent in the vast majority of individuals.

Original languageEnglish (US)
Pages (from-to)257-266
Number of pages10
JournalCNS Drugs
Volume14
Issue number4
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Fingerprint

Lyme Neuroborreliosis
Central Nervous System
Spirochaetales
Borrelia burgdorferi
Lyme Disease
Peripheral Nervous System
Ticks
Communicable Diseases
Joints
Western Blotting
Enzyme-Linked Immunosorbent Assay
Infection
Therapeutics

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Psychiatry and Mental health
  • Pharmacology (medical)

Cite this

Halperin, John. / Lyme neuroborreliosis. In: CNS Drugs. 2000 ; Vol. 14, No. 4. pp. 257-266.
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Lyme neuroborreliosis. / Halperin, John.

In: CNS Drugs, Vol. 14, No. 4, 01.01.2000, p. 257-266.

Research output: Contribution to journalArticle

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