Langerhans cell histiocytosis associated with elevation of angiotensin- converting enzyme levels

Elliot Rosenstein, R. N. Eskow, D. A. Lederman, Neil Kramer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The authors describe a 22-year-old man with osteolytic mandibular and maxillary lesions. Biopsy substantiated the presence of Langerhans cell histiocytosis (eosinophilic granuloma). Levels of serum angiotensin- converting enzyme (ACE) were elevated repeatedly. After definitive therapy with excision and bone grafting, ACE levels returned to normal. The role of histiocytes in ACE production is discussed. Langerhans cell histiocytosis should be considered in the diagnosis of conditions occurring with elevation of serum ACE levels and clinical findings similar to sarcoidosis.

Original languageEnglish (US)
Pages (from-to)65-67
Number of pages3
JournalAmerican Journal of the Medical Sciences
Volume310
Issue number2
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Langerhans Cell Histiocytosis
Peptidyl-Dipeptidase A
Eosinophilic Granuloma
Histiocytes
Bone Transplantation
Sarcoidosis
Serum
Biopsy
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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Langerhans cell histiocytosis associated with elevation of angiotensin- converting enzyme levels. / Rosenstein, Elliot; Eskow, R. N.; Lederman, D. A.; Kramer, Neil.

In: American Journal of the Medical Sciences, Vol. 310, No. 2, 01.01.1995, p. 65-67.

Research output: Contribution to journalArticle

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