Immunoreactive inhibin, mullerian inhibitory substance, and activin as biochemical markers for juvenile granulosa cell tumors

Lawrence Silverman, S. E. Gitelman

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Ovarian juvenile granulosa cell tumors are a rare cause of sexual precocity. Clinical examination, serum estradiol levels, and pelvic imaging studies have been used traditionally to detect such tumors. Immunoassays for mullerian inhibitory substance and inhibin have recently been noted to provide a more sensitive means of tumor detection in adults. We now describe two girls with this type of tumor in whom serum concentrations of inhibin and mullerian inhibitory substance were used as tumor markers.

Original languageEnglish (US)
Pages (from-to)918-921
Number of pages4
JournalJournal of Pediatrics
Volume129
Issue number6
DOIs
StatePublished - Jan 1 1996
Externally publishedYes

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Granulosa Cell Tumor
Anti-Mullerian Hormone
Activins
Inhibins
Biomarkers
Neoplasms
Tumor Biomarkers
Serum
Immunoassay
Estradiol

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

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Immunoreactive inhibin, mullerian inhibitory substance, and activin as biochemical markers for juvenile granulosa cell tumors. / Silverman, Lawrence; Gitelman, S. E.

In: Journal of Pediatrics, Vol. 129, No. 6, 01.01.1996, p. 918-921.

Research output: Contribution to journalArticle

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