IgG Inhibitor of Polymorphonuclear-Leukocyte Motility

Eufronio G. Maderazo, Charles L. Woronick, Ira M. Goldstein, H. Daniel Perez, Neil Kramer

Research output: Contribution to journalLetter

Abstract

To the Editor: In an article in the November 27 issue, Kramer and his co-workers1 reported the presence of a serum inhibitor of polymorphonuclear-leukocyte (PMN) motility in a patient with recurrent infection, and they attributed this inhibitory activity to a noncytotoxic IgG autoantibody to a cell-surface constituent of PMNs. They also noted that IgG and the Fc fragment of IgG from normal serum did not possess this inhibitory activity. This finding is not in keeping with the results that we obtained in our studies with a similar assay system.2 The one possible explanation for this discrepancy is that buffer with.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Volume304
Issue number18
DOIs
StatePublished - Apr 30 1981
Externally publishedYes

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Neutrophils
Immunoglobulin G
Immunoglobulin Fc Fragments
Serum
Autoantibodies
Buffers
Infection

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Maderazo, Eufronio G. ; Woronick, Charles L. ; Goldstein, Ira M. ; Perez, H. Daniel ; Kramer, Neil. / IgG Inhibitor of Polymorphonuclear-Leukocyte Motility. In: New England Journal of Medicine. 1981 ; Vol. 304, No. 18.
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IgG Inhibitor of Polymorphonuclear-Leukocyte Motility. / Maderazo, Eufronio G.; Woronick, Charles L.; Goldstein, Ira M.; Perez, H. Daniel; Kramer, Neil.

In: New England Journal of Medicine, Vol. 304, No. 18, 30.04.1981.

Research output: Contribution to journalLetter

TY - JOUR

T1 - IgG Inhibitor of Polymorphonuclear-Leukocyte Motility

AU - Maderazo, Eufronio G.

AU - Woronick, Charles L.

AU - Goldstein, Ira M.

AU - Perez, H. Daniel

AU - Kramer, Neil

PY - 1981/4/30

Y1 - 1981/4/30

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