Hypodysfibrinogenemia during pregnancy, labor, and delivery

Shad H. Deering, Helain J. Landy, Nana Tchabo, Craig Kessler

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

BACKGROUND: Hypodysfibrinogenemia is an autosomally dominant disorder that can result in excessive bleeding as well as specific pregnancy complications. Increased risks of spontaneous abortion, postpartum hemorrhage, poor wound healing, and placental abruption have been reported. CASE: A woman with hypodysfibrinogenemia presented for care in the first trimester. Her antepartum course was uncomplicated, and she was administered intermediate-purity factor VIII during labor and did not have excessive bleeding postpartum. The infant's cord fibrinogen was low, at 43 mg/dL (normal 215 ± 30), showing it was similarly affected. CONCLUSION: Pregnancy in patients with hypodysfibrinogenemia can be associated with various complications; however, coordination of care and anticipation of specific problems can result in a successful outcome for both mother and infant.

Original languageEnglish (US)
Pages (from-to)1092-1094
Number of pages3
JournalObstetrics and Gynecology
Volume101
Issue number5 SUPPL.
DOIs
StatePublished - May 1 2003
Externally publishedYes

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Hemorrhage
Abruptio Placentae
Postpartum Hemorrhage
Pregnancy
Pregnancy Complications
Factor VIII
Spontaneous Abortion
First Pregnancy Trimester
Wound Healing
Fibrinogen
Postpartum Period
Mothers

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Deering, Shad H. ; Landy, Helain J. ; Tchabo, Nana ; Kessler, Craig. / Hypodysfibrinogenemia during pregnancy, labor, and delivery. In: Obstetrics and Gynecology. 2003 ; Vol. 101, No. 5 SUPPL. pp. 1092-1094.
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Hypodysfibrinogenemia during pregnancy, labor, and delivery. / Deering, Shad H.; Landy, Helain J.; Tchabo, Nana; Kessler, Craig.

In: Obstetrics and Gynecology, Vol. 101, No. 5 SUPPL., 01.05.2003, p. 1092-1094.

Research output: Contribution to journalArticle

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