Abstract
Delay between the initial symptoms, diagnosis, and the definitive treatment of head and neck cancers is associated with tumor progression and upstaging. These delays may lead to poor outcomes and may mandate more aggressive treatments with unnecessary morbidity and even mortality. The multidisciplinary team approach for the treatment of patients with head and neck cancers has improved organization of standard clinical guidelines, but this development has yet to translate into a demonstrable impact on survival. We review the association between waiting times (time between diagnosis and initiation of treatment) and clinical outcomes in patients with head and neck squamous cell carcinoma (HNSCC).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 153-160 |
| Number of pages | 8 |
| Journal | Advances in Therapy |
| Volume | 35 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2018 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
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Head and Neck Cancer : A Review of the Impact of Treatment Delay on Outcome. / Coca-Pelaz, Andrés; Takes, Robert P.; Hutcheson, Kate; Saba, Nabil F.; Haigentz, Missak; Bradford, Carol R.; de Bree, Remco; Strojan, Primož; Lund, Valerie J.; Mendenhall, William M.; Nixon, Iain J.; Quer, Miquel; Rinaldo, Alessandra; Ferlito, Alfio.
In: Advances in Therapy, Vol. 35, No. 2, 01.02.2018, p. 153-160.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Head and Neck Cancer
T2 - A Review of the Impact of Treatment Delay on Outcome
AU - Coca-Pelaz, Andrés
AU - Takes, Robert P.
AU - Hutcheson, Kate
AU - Saba, Nabil F.
AU - Haigentz, Missak
AU - Bradford, Carol R.
AU - de Bree, Remco
AU - Strojan, Primož
AU - Lund, Valerie J.
AU - Mendenhall, William M.
AU - Nixon, Iain J.
AU - Quer, Miquel
AU - Rinaldo, Alessandra
AU - Ferlito, Alfio
PY - 2018/2/1
Y1 - 2018/2/1
N2 - Delay between the initial symptoms, diagnosis, and the definitive treatment of head and neck cancers is associated with tumor progression and upstaging. These delays may lead to poor outcomes and may mandate more aggressive treatments with unnecessary morbidity and even mortality. The multidisciplinary team approach for the treatment of patients with head and neck cancers has improved organization of standard clinical guidelines, but this development has yet to translate into a demonstrable impact on survival. We review the association between waiting times (time between diagnosis and initiation of treatment) and clinical outcomes in patients with head and neck squamous cell carcinoma (HNSCC).
AB - Delay between the initial symptoms, diagnosis, and the definitive treatment of head and neck cancers is associated with tumor progression and upstaging. These delays may lead to poor outcomes and may mandate more aggressive treatments with unnecessary morbidity and even mortality. The multidisciplinary team approach for the treatment of patients with head and neck cancers has improved organization of standard clinical guidelines, but this development has yet to translate into a demonstrable impact on survival. We review the association between waiting times (time between diagnosis and initiation of treatment) and clinical outcomes in patients with head and neck squamous cell carcinoma (HNSCC).
UR - http://www.scopus.com/inward/record.url?scp=85042231065&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85042231065&partnerID=8YFLogxK
U2 - 10.1007/s12325-018-0663-7
DO - 10.1007/s12325-018-0663-7
M3 - Review article
C2 - 29396681
AN - SCOPUS:85042231065
VL - 35
SP - 153
EP - 160
JO - Advances in Therapy
JF - Advances in Therapy
SN - 0741-238X
IS - 2
ER -