Head and Neck Cancer: A Review of the Impact of Treatment Delay on Outcome

Andrés Coca-Pelaz, Robert P. Takes, Kate Hutcheson, Nabil F. Saba, Missak Haigentz, Carol R. Bradford, Remco de Bree, Primož Strojan, Valerie J. Lund, William M. Mendenhall, Iain J. Nixon, Miquel Quer, Alessandra Rinaldo, Alfio Ferlito

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Delay between the initial symptoms, diagnosis, and the definitive treatment of head and neck cancers is associated with tumor progression and upstaging. These delays may lead to poor outcomes and may mandate more aggressive treatments with unnecessary morbidity and even mortality. The multidisciplinary team approach for the treatment of patients with head and neck cancers has improved organization of standard clinical guidelines, but this development has yet to translate into a demonstrable impact on survival. We review the association between waiting times (time between diagnosis and initiation of treatment) and clinical outcomes in patients with head and neck squamous cell carcinoma (HNSCC).

Original languageEnglish (US)
Pages (from-to)153-160
Number of pages8
JournalAdvances in Therapy
Volume35
Issue number2
DOIs
StatePublished - Feb 1 2018
Externally publishedYes

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Head and Neck Neoplasms
Therapeutics
Organizations
Guidelines
Morbidity
Survival
Mortality
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pharmacology (medical)

Cite this

Coca-Pelaz, A., Takes, R. P., Hutcheson, K., Saba, N. F., Haigentz, M., Bradford, C. R., ... Ferlito, A. (2018). Head and Neck Cancer: A Review of the Impact of Treatment Delay on Outcome. Advances in Therapy, 35(2), 153-160. https://doi.org/10.1007/s12325-018-0663-7
Coca-Pelaz, Andrés ; Takes, Robert P. ; Hutcheson, Kate ; Saba, Nabil F. ; Haigentz, Missak ; Bradford, Carol R. ; de Bree, Remco ; Strojan, Primož ; Lund, Valerie J. ; Mendenhall, William M. ; Nixon, Iain J. ; Quer, Miquel ; Rinaldo, Alessandra ; Ferlito, Alfio. / Head and Neck Cancer : A Review of the Impact of Treatment Delay on Outcome. In: Advances in Therapy. 2018 ; Vol. 35, No. 2. pp. 153-160.
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Coca-Pelaz, A, Takes, RP, Hutcheson, K, Saba, NF, Haigentz, M, Bradford, CR, de Bree, R, Strojan, P, Lund, VJ, Mendenhall, WM, Nixon, IJ, Quer, M, Rinaldo, A & Ferlito, A 2018, 'Head and Neck Cancer: A Review of the Impact of Treatment Delay on Outcome', Advances in Therapy, vol. 35, no. 2, pp. 153-160. https://doi.org/10.1007/s12325-018-0663-7

Head and Neck Cancer : A Review of the Impact of Treatment Delay on Outcome. / Coca-Pelaz, Andrés; Takes, Robert P.; Hutcheson, Kate; Saba, Nabil F.; Haigentz, Missak; Bradford, Carol R.; de Bree, Remco; Strojan, Primož; Lund, Valerie J.; Mendenhall, William M.; Nixon, Iain J.; Quer, Miquel; Rinaldo, Alessandra; Ferlito, Alfio.

In: Advances in Therapy, Vol. 35, No. 2, 01.02.2018, p. 153-160.

Research output: Contribution to journalReview article

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AU - Coca-Pelaz, Andrés

AU - Takes, Robert P.

AU - Hutcheson, Kate

AU - Saba, Nabil F.

AU - Haigentz, Missak

AU - Bradford, Carol R.

AU - de Bree, Remco

AU - Strojan, Primož

AU - Lund, Valerie J.

AU - Mendenhall, William M.

AU - Nixon, Iain J.

AU - Quer, Miquel

AU - Rinaldo, Alessandra

AU - Ferlito, Alfio

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