Familial bilateral carpal tunnel syndrome: Report of two families

Dana Leifer, Didier Cros, John J. Halperin, G. Gregory Gallico, Donald S. Pierce, Bhagwan T. Shahani

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Cases of familial carpal tunnel syndrome without other associated conditions are rare. We report two families in which multiple members had bilateral carpal tunnel syndromes. The pattern was consistent with autosomal dominant inheritance. Electrophysologic studies were performed on nine of the 15 patients, and they demonstrated bilateral pathology of the median nerves at the wrist in all but one patient, without evidence for subclinical, generalized peripheral neuropathy. Quantitative sensory testing was performed in two cases, and it corroborated the absence of peripheral neuropathy. Five of the six patients who underwent carpal tunnel release improved after surgery.

Original languageEnglish (US)
Pages (from-to)393-397
Number of pages5
JournalArchives of Physical Medicine and Rehabilitation
Volume73
Issue number4
DOIs
StatePublished - Apr 1992
Externally publishedYes

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Carpal Tunnel Syndrome
Peripheral Nervous System Diseases
Wrist
Median Nerve
Pathology

All Science Journal Classification (ASJC) codes

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

Cite this

Leifer, Dana ; Cros, Didier ; Halperin, John J. ; Gregory Gallico, G. ; Pierce, Donald S. ; Shahani, Bhagwan T. / Familial bilateral carpal tunnel syndrome : Report of two families. In: Archives of Physical Medicine and Rehabilitation. 1992 ; Vol. 73, No. 4. pp. 393-397.
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Familial bilateral carpal tunnel syndrome : Report of two families. / Leifer, Dana; Cros, Didier; Halperin, John J.; Gregory Gallico, G.; Pierce, Donald S.; Shahani, Bhagwan T.

In: Archives of Physical Medicine and Rehabilitation, Vol. 73, No. 4, 04.1992, p. 393-397.

Research output: Contribution to journalArticle

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