Evaluating cervical neoplasia

LEEP as an alternative to cold knife conization

Jeané R. Simmons, Lisa Anderson, Enrique Hernandez, Paul Heller

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

OBJECTIVE: To determine how the loop electrosurgical excision procedure (LEEP) compares to cold knife conization in providing an adequate diagnostic specimen. STUDY DESIGN: Between 1991 and 1995, 95 patients underwent either diagnostic LEEP or cold knife conization at Allegheny University Hospitals. The indications for the procedure were a cytologic/histologic discrepancy, unsatisfactory colposcopic evaluation, positive endocervical curettage or exclusion of invasion. RESULTS: Severe thermal artifact rendered the LEEP specimens uninterpretable in 4.4% of cases. A median number of two passes were required for LEEP excision of the transformation zone. The number of passes correlated with the amount of thermal artifact detected (P=.034). Regarding recurrence patterns, normal follow-up cervical cytology was similar for both groups: 96.7% in the LEEP group vs. 100% in the cold knife conization group. CONCLUSION: We conclude that LEEP is an acceptable diagnostic alternative to traditional cold knife conization. Thermal artifact remains a disadvantage that can be minimized by limiting the number of passes required to obtain a complete specimen.

Original languageEnglish (US)
Pages (from-to)1007-1014
Number of pages8
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume43
Issue number12
StatePublished - Dec 1 1998
Externally publishedYes

Fingerprint

Conization
Neoplasms
Artifacts
Hot Temperature
Curettage
Cell Biology
Recurrence

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

@article{c4cafea3b4f244529720da11af829b88,
title = "Evaluating cervical neoplasia: LEEP as an alternative to cold knife conization",
abstract = "OBJECTIVE: To determine how the loop electrosurgical excision procedure (LEEP) compares to cold knife conization in providing an adequate diagnostic specimen. STUDY DESIGN: Between 1991 and 1995, 95 patients underwent either diagnostic LEEP or cold knife conization at Allegheny University Hospitals. The indications for the procedure were a cytologic/histologic discrepancy, unsatisfactory colposcopic evaluation, positive endocervical curettage or exclusion of invasion. RESULTS: Severe thermal artifact rendered the LEEP specimens uninterpretable in 4.4{\%} of cases. A median number of two passes were required for LEEP excision of the transformation zone. The number of passes correlated with the amount of thermal artifact detected (P=.034). Regarding recurrence patterns, normal follow-up cervical cytology was similar for both groups: 96.7{\%} in the LEEP group vs. 100{\%} in the cold knife conization group. CONCLUSION: We conclude that LEEP is an acceptable diagnostic alternative to traditional cold knife conization. Thermal artifact remains a disadvantage that can be minimized by limiting the number of passes required to obtain a complete specimen.",
author = "Simmons, {Jean{\'e} R.} and Lisa Anderson and Enrique Hernandez and Paul Heller",
year = "1998",
month = "12",
day = "1",
language = "English (US)",
volume = "43",
pages = "1007--1014",
journal = "The Journal of reproductive medicine",
issn = "0024-7758",
publisher = "Donna Kessel",
number = "12",

}

Evaluating cervical neoplasia : LEEP as an alternative to cold knife conization. / Simmons, Jeané R.; Anderson, Lisa; Hernandez, Enrique; Heller, Paul.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 43, No. 12, 01.12.1998, p. 1007-1014.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Evaluating cervical neoplasia

T2 - LEEP as an alternative to cold knife conization

AU - Simmons, Jeané R.

AU - Anderson, Lisa

AU - Hernandez, Enrique

AU - Heller, Paul

PY - 1998/12/1

Y1 - 1998/12/1

N2 - OBJECTIVE: To determine how the loop electrosurgical excision procedure (LEEP) compares to cold knife conization in providing an adequate diagnostic specimen. STUDY DESIGN: Between 1991 and 1995, 95 patients underwent either diagnostic LEEP or cold knife conization at Allegheny University Hospitals. The indications for the procedure were a cytologic/histologic discrepancy, unsatisfactory colposcopic evaluation, positive endocervical curettage or exclusion of invasion. RESULTS: Severe thermal artifact rendered the LEEP specimens uninterpretable in 4.4% of cases. A median number of two passes were required for LEEP excision of the transformation zone. The number of passes correlated with the amount of thermal artifact detected (P=.034). Regarding recurrence patterns, normal follow-up cervical cytology was similar for both groups: 96.7% in the LEEP group vs. 100% in the cold knife conization group. CONCLUSION: We conclude that LEEP is an acceptable diagnostic alternative to traditional cold knife conization. Thermal artifact remains a disadvantage that can be minimized by limiting the number of passes required to obtain a complete specimen.

AB - OBJECTIVE: To determine how the loop electrosurgical excision procedure (LEEP) compares to cold knife conization in providing an adequate diagnostic specimen. STUDY DESIGN: Between 1991 and 1995, 95 patients underwent either diagnostic LEEP or cold knife conization at Allegheny University Hospitals. The indications for the procedure were a cytologic/histologic discrepancy, unsatisfactory colposcopic evaluation, positive endocervical curettage or exclusion of invasion. RESULTS: Severe thermal artifact rendered the LEEP specimens uninterpretable in 4.4% of cases. A median number of two passes were required for LEEP excision of the transformation zone. The number of passes correlated with the amount of thermal artifact detected (P=.034). Regarding recurrence patterns, normal follow-up cervical cytology was similar for both groups: 96.7% in the LEEP group vs. 100% in the cold knife conization group. CONCLUSION: We conclude that LEEP is an acceptable diagnostic alternative to traditional cold knife conization. Thermal artifact remains a disadvantage that can be minimized by limiting the number of passes required to obtain a complete specimen.

UR - http://www.scopus.com/inward/record.url?scp=0032432292&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032432292&partnerID=8YFLogxK

M3 - Article

VL - 43

SP - 1007

EP - 1014

JO - The Journal of reproductive medicine

JF - The Journal of reproductive medicine

SN - 0024-7758

IS - 12

ER -