Erectile dysfunction following minimally invasive treatments for prostate cancer

David Chaikin, Gregory A. Broderick, Terrence R. Malloy, S. Bruce Malkowicz, Richard Whittington, Alan J. Wein

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Objectives. Cryosurgical ablation of the prostate (CSAP) and interstitial radiotherapy (IR) are relatively new procedures intended to be less invasive than radical prostatectomy for the treatment of prostate cancer. Despite absence of long-term or intermediate data on efficacy, many patients choose one of these therapies because they presume their potency will be maintained. We report our experience with CSAP, IR, and postprocedure erectile dysfunction. Methods. Global sexual assessments were made at 12 months after therapy in 28 CSAP patients, and at 18 months in 37 IR patients. Each patient was contacted by telephone following his procedure. The patients were asked several questions regarding their sexual function both preoperatively and postoperatively. The questionnaire was administered only to the patient. Results. Twenty-eight of 36 patients who underwent CSAP responded to the questionnaire (78%). Twenty patients were potent preoperatively (71%). The mean age of the potent group was 69 years (range 54 to 82). Following therapy, 2 of these patients (10%) reported potency at 12 months. Thirty-seven of 42 patients who underwent IR responded to the questionnaire (88%). Twenty-seven were potent preoperatively (73%). The mean age of the potent group was 70 years (range 56 to 83). The mean follow-up was 18 months (range 5 to 36). Following therapy, 15 patients reported potency (55%). All of the patients who reported potency felt that the quality of their erections had decreased following radiation. Conclusions. Our short- term results with IR and CSAP suggest a significant adverse effect on erectile function. Our results suggest that enhanced preservation of potency should not be used as an enticement in the promotion of IR or CSAP.

Original languageEnglish (US)
Pages (from-to)100-104
Number of pages5
JournalUrology
Volume48
Issue number1
DOIs
StatePublished - Jan 1 1996

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Erectile Dysfunction
Prostatic Neoplasms
Brachytherapy
Prostate
Therapeutics
Age Groups
Prostatectomy
Telephone
Radiation

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Chaikin, D., Broderick, G. A., Malloy, T. R., Malkowicz, S. B., Whittington, R., & Wein, A. J. (1996). Erectile dysfunction following minimally invasive treatments for prostate cancer. Urology, 48(1), 100-104. https://doi.org/10.1016/S0090-4295(96)00088-X
Chaikin, David ; Broderick, Gregory A. ; Malloy, Terrence R. ; Malkowicz, S. Bruce ; Whittington, Richard ; Wein, Alan J. / Erectile dysfunction following minimally invasive treatments for prostate cancer. In: Urology. 1996 ; Vol. 48, No. 1. pp. 100-104.
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Chaikin, D, Broderick, GA, Malloy, TR, Malkowicz, SB, Whittington, R & Wein, AJ 1996, 'Erectile dysfunction following minimally invasive treatments for prostate cancer', Urology, vol. 48, no. 1, pp. 100-104. https://doi.org/10.1016/S0090-4295(96)00088-X

Erectile dysfunction following minimally invasive treatments for prostate cancer. / Chaikin, David; Broderick, Gregory A.; Malloy, Terrence R.; Malkowicz, S. Bruce; Whittington, Richard; Wein, Alan J.

In: Urology, Vol. 48, No. 1, 01.01.1996, p. 100-104.

Research output: Contribution to journalArticle

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T1 - Erectile dysfunction following minimally invasive treatments for prostate cancer

AU - Chaikin, David

AU - Broderick, Gregory A.

AU - Malloy, Terrence R.

AU - Malkowicz, S. Bruce

AU - Whittington, Richard

AU - Wein, Alan J.

PY - 1996/1/1

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N2 - Objectives. Cryosurgical ablation of the prostate (CSAP) and interstitial radiotherapy (IR) are relatively new procedures intended to be less invasive than radical prostatectomy for the treatment of prostate cancer. Despite absence of long-term or intermediate data on efficacy, many patients choose one of these therapies because they presume their potency will be maintained. We report our experience with CSAP, IR, and postprocedure erectile dysfunction. Methods. Global sexual assessments were made at 12 months after therapy in 28 CSAP patients, and at 18 months in 37 IR patients. Each patient was contacted by telephone following his procedure. The patients were asked several questions regarding their sexual function both preoperatively and postoperatively. The questionnaire was administered only to the patient. Results. Twenty-eight of 36 patients who underwent CSAP responded to the questionnaire (78%). Twenty patients were potent preoperatively (71%). The mean age of the potent group was 69 years (range 54 to 82). Following therapy, 2 of these patients (10%) reported potency at 12 months. Thirty-seven of 42 patients who underwent IR responded to the questionnaire (88%). Twenty-seven were potent preoperatively (73%). The mean age of the potent group was 70 years (range 56 to 83). The mean follow-up was 18 months (range 5 to 36). Following therapy, 15 patients reported potency (55%). All of the patients who reported potency felt that the quality of their erections had decreased following radiation. Conclusions. Our short- term results with IR and CSAP suggest a significant adverse effect on erectile function. Our results suggest that enhanced preservation of potency should not be used as an enticement in the promotion of IR or CSAP.

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Chaikin D, Broderick GA, Malloy TR, Malkowicz SB, Whittington R, Wein AJ. Erectile dysfunction following minimally invasive treatments for prostate cancer. Urology. 1996 Jan 1;48(1):100-104. https://doi.org/10.1016/S0090-4295(96)00088-X