Does air travel affect pregnancy outcome?

Mala Freeman, Alessandro Ghidini, Catherine Y. Spong, Nana Tchabo, Patricia Z. Bannon, John C. Pezzullo

Research output: Contribution to journalReview article

16 Citations (Scopus)

Abstract

Methods: To evaluate if air travel affects pregnancy outcome, all women with singleton, non anomalous fetuses, admitted for delivery at a gestational age >20.0 weeks over a 6-month period were asked if they traveled by airflight during pregnancy, including details of the destination and length of their flights and any complications during the travel. Pregnancy outcome was obtained by chart review. Statistical analysis included Student's t-test, Mann-Whitney U test, chi square, Fisher's exact test where appropriate, and linear and logistic regression analysis, with p <0.05 considered significant. Results: Two hundred twenty-two women were studied. Of these, 53% (n=118) traveled at least once during pregnancy (median 2 flights, range 1-12). The first flight was taken at a mean ± standard deviation gestational age of 13.3±7.6 weeks with average flight lasting 4±2 h. There were no differences in gestational age at delivery (39.1 vs. 38.4 weeks, p=0.07), neonatal birthweight (3,379 vs. 3,273 g, p=0.24), or rates of vaginal bleeding (2% vs. 5%, p=0.26), preterm delivery <37 weeks (9% vs. 14%, p=0.29), preeclampsia (5% vs. 6%, p=0.76), neonatal intensive care unit admission (13% vs. 16%, p=0.56), or cumulative adverse obstetric outcome (p=0.61) between those who did and did not air travel during pregnancy. Power analysis demonstrated that a sample size of 2,803 women in each group would be necessary to show that air travel has a protective effect against adverse pregnancy outcome (alpha = 0.05, beta = 0.80). There were no thromboembolic events complicating any of the pregnancies. Conclusion: Our findings suggest that air travel is not associated with increased risk of complications for pregnancies that reach 20 weeks' gestation.

Original languageEnglish (US)
Pages (from-to)274-277
Number of pages4
JournalArchives of Gynecology and Obstetrics
Volume269
Issue number4
DOIs
StatePublished - Jan 1 2004
Externally publishedYes

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Air Travel
Pregnancy Outcome
Pregnancy
Gestational Age
Pregnancy Complications
Uterine Hemorrhage
Neonatal Intensive Care Units
Nonparametric Statistics
Pre-Eclampsia
Sample Size
Obstetrics
Linear Models
Fetus
Logistic Models
Regression Analysis
Students

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Freeman, M., Ghidini, A., Spong, C. Y., Tchabo, N., Bannon, P. Z., & Pezzullo, J. C. (2004). Does air travel affect pregnancy outcome? Archives of Gynecology and Obstetrics, 269(4), 274-277. https://doi.org/10.1007/s00404-003-0579-5
Freeman, Mala ; Ghidini, Alessandro ; Spong, Catherine Y. ; Tchabo, Nana ; Bannon, Patricia Z. ; Pezzullo, John C. / Does air travel affect pregnancy outcome?. In: Archives of Gynecology and Obstetrics. 2004 ; Vol. 269, No. 4. pp. 274-277.
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Freeman, M, Ghidini, A, Spong, CY, Tchabo, N, Bannon, PZ & Pezzullo, JC 2004, 'Does air travel affect pregnancy outcome?', Archives of Gynecology and Obstetrics, vol. 269, no. 4, pp. 274-277. https://doi.org/10.1007/s00404-003-0579-5

Does air travel affect pregnancy outcome? / Freeman, Mala; Ghidini, Alessandro; Spong, Catherine Y.; Tchabo, Nana; Bannon, Patricia Z.; Pezzullo, John C.

In: Archives of Gynecology and Obstetrics, Vol. 269, No. 4, 01.01.2004, p. 274-277.

Research output: Contribution to journalReview article

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T1 - Does air travel affect pregnancy outcome?

AU - Freeman, Mala

AU - Ghidini, Alessandro

AU - Spong, Catherine Y.

AU - Tchabo, Nana

AU - Bannon, Patricia Z.

AU - Pezzullo, John C.

PY - 2004/1/1

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N2 - Methods: To evaluate if air travel affects pregnancy outcome, all women with singleton, non anomalous fetuses, admitted for delivery at a gestational age >20.0 weeks over a 6-month period were asked if they traveled by airflight during pregnancy, including details of the destination and length of their flights and any complications during the travel. Pregnancy outcome was obtained by chart review. Statistical analysis included Student's t-test, Mann-Whitney U test, chi square, Fisher's exact test where appropriate, and linear and logistic regression analysis, with p <0.05 considered significant. Results: Two hundred twenty-two women were studied. Of these, 53% (n=118) traveled at least once during pregnancy (median 2 flights, range 1-12). The first flight was taken at a mean ± standard deviation gestational age of 13.3±7.6 weeks with average flight lasting 4±2 h. There were no differences in gestational age at delivery (39.1 vs. 38.4 weeks, p=0.07), neonatal birthweight (3,379 vs. 3,273 g, p=0.24), or rates of vaginal bleeding (2% vs. 5%, p=0.26), preterm delivery <37 weeks (9% vs. 14%, p=0.29), preeclampsia (5% vs. 6%, p=0.76), neonatal intensive care unit admission (13% vs. 16%, p=0.56), or cumulative adverse obstetric outcome (p=0.61) between those who did and did not air travel during pregnancy. Power analysis demonstrated that a sample size of 2,803 women in each group would be necessary to show that air travel has a protective effect against adverse pregnancy outcome (alpha = 0.05, beta = 0.80). There were no thromboembolic events complicating any of the pregnancies. Conclusion: Our findings suggest that air travel is not associated with increased risk of complications for pregnancies that reach 20 weeks' gestation.

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Freeman M, Ghidini A, Spong CY, Tchabo N, Bannon PZ, Pezzullo JC. Does air travel affect pregnancy outcome? Archives of Gynecology and Obstetrics. 2004 Jan 1;269(4):274-277. https://doi.org/10.1007/s00404-003-0579-5