Diagnosis and treatment of the neuromuscular manifestations of Lyme disease

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Although estimates vary, the nervous system appears to be involved in 10% to 15% of patients infected with Borrelia burgdorferi. The resulting disorders, known collectively as neuroborreliosis or nervous system Lyme disease, generally respond well to antimicrobial therapy. Definitive treatment of nervous system infection typically consists of 2 to 4 weeks of parenteral ceftriaxone, cefotaxime, or high-dose penicillin (Class III). However, numerous European studies have shown that oral doxycycline is equally effective in patients with Lyme meningitis and cranial neuritis (Class II and III). This may be equally valid in patients infected with the strains prevalent in the United States, but this remains to be established.

Original languageEnglish (US)
Pages (from-to)93-100
Number of pages8
JournalCurrent Treatment Options in Neurology
Volume9
Issue number2
DOIs
StatePublished - Mar 1 2007
Externally publishedYes

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Neuromuscular Manifestations
Lyme Disease
Nervous System
Lyme Neuroborreliosis
Neuritis
Borrelia burgdorferi
Cefotaxime
Ceftriaxone
Doxycycline
Meningitis
Penicillins
Therapeutics
Infection

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

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Diagnosis and treatment of the neuromuscular manifestations of Lyme disease. / Halperin, John.

In: Current Treatment Options in Neurology, Vol. 9, No. 2, 01.03.2007, p. 93-100.

Research output: Contribution to journalReview article

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