Diagnosis and management of acute encephalitis

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Encephalitis is typically viral (approximately half of diagnosed cases) or autoimmune (about a quarter) with the remainder remaining undiagnosable at this time. All require general supportive care but only a minority requires intensive care admission – in these intubation, to protect the airway or to treat status epilepticus with anesthetic drugs, may be needed. In some dysautonomia with wide blood pressure fluctuations is the principal concern. Remarkably, in addition to supportive care, specific treatment options are available for the majority – immune-modulating therapy for those with autoimmune disorders, antiviral therapy for herpes simplex 1 and 2, and varicella-zoster encephalitis. Flavivirus infections (West Nile, Japanese encephalitis, tick-borne encephalitis) remain the most common other identified cause of encephalitis but no specific intervention is available. Overall long-term outcomes are favorable in the majority of patients with encephalitis, a proportion that hopefully will improve with further advances in diagnostic technology and therapeutic interventions.

Original languageEnglish (US)
Title of host publicationHandbook of Clinical Neurology
PublisherElsevier B.V.
Pages337-347
Number of pages11
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Publication series

NameHandbook of Clinical Neurology
Volume140
ISSN (Print)0072-9752
ISSN (Electronic)2212-4152

Fingerprint

Encephalitis
Varicella Zoster Encephalitis
Flavivirus Infections
Primary Dysautonomias
Japanese Encephalitis
Tick-Borne Encephalitis
Herpes Simplex
Status Epilepticus
Therapeutics
Critical Care
Intubation
Antiviral Agents
Anesthetics
Blood Pressure
Technology

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

Cite this

Halperin, J. J. (2017). Diagnosis and management of acute encephalitis. In Handbook of Clinical Neurology (pp. 337-347). (Handbook of Clinical Neurology; Vol. 140). Elsevier B.V.. https://doi.org/10.1016/B978-0-444-63600-3.00018-0
Halperin, J. J. / Diagnosis and management of acute encephalitis. Handbook of Clinical Neurology. Elsevier B.V., 2017. pp. 337-347 (Handbook of Clinical Neurology).
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Halperin, JJ 2017, Diagnosis and management of acute encephalitis. in Handbook of Clinical Neurology. Handbook of Clinical Neurology, vol. 140, Elsevier B.V., pp. 337-347. https://doi.org/10.1016/B978-0-444-63600-3.00018-0

Diagnosis and management of acute encephalitis. / Halperin, J. J.

Handbook of Clinical Neurology. Elsevier B.V., 2017. p. 337-347 (Handbook of Clinical Neurology; Vol. 140).

Research output: Chapter in Book/Report/Conference proceedingChapter

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Halperin JJ. Diagnosis and management of acute encephalitis. In Handbook of Clinical Neurology. Elsevier B.V. 2017. p. 337-347. (Handbook of Clinical Neurology). https://doi.org/10.1016/B978-0-444-63600-3.00018-0