Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass

M. C. Oz, James Slater, N. Edwards, M. L. Dickstein, J. R. Beck, H. M. Spotnitz, H. R. Levin

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Right-sided circulatory failure is a major cause of morbidity in heart transplant and ventricular assist device recipients. Methods: Several systems for managing right-sided circulatory failure with use of a right-to-left shunt without need for an oxygenator or systemic heparinization were designed and used clinically. Results: A right-to-left shunt was successfully used to treat severe right-sided circulatory failure in both a transplant and a left ventricular assist device recipient. Conclusions: If constructed between the femoral vein and artery, such a shunt could (1) be easily inserted and removed, (2) selectively infuse the lower extremities with desaturated blood while maintaining cerebral and cardiac perfusion with saturated blood, (3) selectively reduce the risk of paradoxical emboli to the head and heart, and (4) provide a known and adjustable degree of shunting depending on the condition of the patient, a major advantage of this system compared with creation of an atrial septal defect.

Original languageEnglish (US)
Pages (from-to)172-176
Number of pages5
JournalJournal of Heart and Lung Transplantation
Volume14
Issue number1 I
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Heart-Assist Devices
Cardiopulmonary Bypass
Shock
Heart Failure
Oxygenators
Transplants
Femoral Vein
Atrial Heart Septal Defects
Femoral Artery
Embolism
Lower Extremity
Perfusion
Head
Morbidity

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Transplantation

Cite this

Oz, M. C., Slater, J., Edwards, N., Dickstein, M. L., Beck, J. R., Spotnitz, H. M., & Levin, H. R. (1995). Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass. Journal of Heart and Lung Transplantation, 14(1 I), 172-176.
Oz, M. C. ; Slater, James ; Edwards, N. ; Dickstein, M. L. ; Beck, J. R. ; Spotnitz, H. M. ; Levin, H. R. / Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass. In: Journal of Heart and Lung Transplantation. 1995 ; Vol. 14, No. 1 I. pp. 172-176.
@article{5317af48b1844a4f9cda2e9c10c6e75b,
title = "Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass",
abstract = "Background: Right-sided circulatory failure is a major cause of morbidity in heart transplant and ventricular assist device recipients. Methods: Several systems for managing right-sided circulatory failure with use of a right-to-left shunt without need for an oxygenator or systemic heparinization were designed and used clinically. Results: A right-to-left shunt was successfully used to treat severe right-sided circulatory failure in both a transplant and a left ventricular assist device recipient. Conclusions: If constructed between the femoral vein and artery, such a shunt could (1) be easily inserted and removed, (2) selectively infuse the lower extremities with desaturated blood while maintaining cerebral and cardiac perfusion with saturated blood, (3) selectively reduce the risk of paradoxical emboli to the head and heart, and (4) provide a known and adjustable degree of shunting depending on the condition of the patient, a major advantage of this system compared with creation of an atrial septal defect.",
author = "Oz, {M. C.} and James Slater and N. Edwards and Dickstein, {M. L.} and Beck, {J. R.} and Spotnitz, {H. M.} and Levin, {H. R.}",
year = "1995",
month = "1",
day = "1",
language = "English (US)",
volume = "14",
pages = "172--176",
journal = "Journal of Heart and Lung Transplantation",
issn = "1053-2498",
publisher = "Elsevier USA",
number = "1 I",

}

Oz, MC, Slater, J, Edwards, N, Dickstein, ML, Beck, JR, Spotnitz, HM & Levin, HR 1995, 'Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass', Journal of Heart and Lung Transplantation, vol. 14, no. 1 I, pp. 172-176.

Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass. / Oz, M. C.; Slater, James; Edwards, N.; Dickstein, M. L.; Beck, J. R.; Spotnitz, H. M.; Levin, H. R.

In: Journal of Heart and Lung Transplantation, Vol. 14, No. 1 I, 01.01.1995, p. 172-176.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass

AU - Oz, M. C.

AU - Slater, James

AU - Edwards, N.

AU - Dickstein, M. L.

AU - Beck, J. R.

AU - Spotnitz, H. M.

AU - Levin, H. R.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Background: Right-sided circulatory failure is a major cause of morbidity in heart transplant and ventricular assist device recipients. Methods: Several systems for managing right-sided circulatory failure with use of a right-to-left shunt without need for an oxygenator or systemic heparinization were designed and used clinically. Results: A right-to-left shunt was successfully used to treat severe right-sided circulatory failure in both a transplant and a left ventricular assist device recipient. Conclusions: If constructed between the femoral vein and artery, such a shunt could (1) be easily inserted and removed, (2) selectively infuse the lower extremities with desaturated blood while maintaining cerebral and cardiac perfusion with saturated blood, (3) selectively reduce the risk of paradoxical emboli to the head and heart, and (4) provide a known and adjustable degree of shunting depending on the condition of the patient, a major advantage of this system compared with creation of an atrial septal defect.

AB - Background: Right-sided circulatory failure is a major cause of morbidity in heart transplant and ventricular assist device recipients. Methods: Several systems for managing right-sided circulatory failure with use of a right-to-left shunt without need for an oxygenator or systemic heparinization were designed and used clinically. Results: A right-to-left shunt was successfully used to treat severe right-sided circulatory failure in both a transplant and a left ventricular assist device recipient. Conclusions: If constructed between the femoral vein and artery, such a shunt could (1) be easily inserted and removed, (2) selectively infuse the lower extremities with desaturated blood while maintaining cerebral and cardiac perfusion with saturated blood, (3) selectively reduce the risk of paradoxical emboli to the head and heart, and (4) provide a known and adjustable degree of shunting depending on the condition of the patient, a major advantage of this system compared with creation of an atrial septal defect.

UR - http://www.scopus.com/inward/record.url?scp=0028952536&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028952536&partnerID=8YFLogxK

M3 - Article

VL - 14

SP - 172

EP - 176

JO - Journal of Heart and Lung Transplantation

JF - Journal of Heart and Lung Transplantation

SN - 1053-2498

IS - 1 I

ER -