Cyclic strain stimulates intracellular superoxide production in vascular smooth muscle cells

George A. Vlastos, Marc Goldschmidt, Dan Sorescu, W. Robert Taylor

Research output: Contribution to journalConference article

Abstract

The effect of cyclic strain on intracellular superoxide production in rat vascular smooth muscle cells (VSMCs) was studied. Cells were examined under a confocal microscope or they were removed from the membranes and the mean intensity per cell was measured with flow cytometry. Data indicate that a short-term application of a 10% cyclic strain in vitro causes an acute increase in intracellular superoxide production in vascular smooth muscle cells.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Externally publishedYes
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

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Muscle
Cells
Flow cytometry
Rats
Microscopes
Membranes

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

Cite this

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Cyclic strain stimulates intracellular superoxide production in vascular smooth muscle cells. / Vlastos, George A.; Goldschmidt, Marc; Sorescu, Dan; Taylor, W. Robert.

In: Annals of Biomedical Engineering, Vol. 28, No. SUPPL. 1, 01.12.2000.

Research output: Contribution to journalConference article

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AU - Goldschmidt, Marc

AU - Sorescu, Dan

AU - Taylor, W. Robert

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N2 - The effect of cyclic strain on intracellular superoxide production in rat vascular smooth muscle cells (VSMCs) was studied. Cells were examined under a confocal microscope or they were removed from the membranes and the mean intensity per cell was measured with flow cytometry. Data indicate that a short-term application of a 10% cyclic strain in vitro causes an acute increase in intracellular superoxide production in vascular smooth muscle cells.

AB - The effect of cyclic strain on intracellular superoxide production in rat vascular smooth muscle cells (VSMCs) was studied. Cells were examined under a confocal microscope or they were removed from the membranes and the mean intensity per cell was measured with flow cytometry. Data indicate that a short-term application of a 10% cyclic strain in vitro causes an acute increase in intracellular superoxide production in vascular smooth muscle cells.

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