Colonic involvement in angioimmunoblastic lymphadenopathy resembling inflammatory bowel disease

Elliot D. Rosenstein, Robert R. Rickert, Michael Gutkin, Angelito Bacay, Neil Kramer

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A woman 68 years of age had fever, malaise, diffuse lymphadenopathy, splenomegaly followed by abdominal pain, and diarrhea. A lymph node biopsy specimen showed nonspecific follicular hyperplasia. Symptoms were responsive initially to prednisone. Recurrent symptoms warranted colonic biopsy, which was consistent with Crohn's disease, and were responsive partially to prednisone and azulfidine. Because of progressive deterioration, a repeat lymph node biopsy was performed and showed the characteristic histologic feature of angioimmunoblastic lymphadenopathy (AILD). The evolution of the histopathologic features of the case is discussed, and gastrointestinal (GI) manifestations of AILD are reviewed. Although the GI tract is an unusual site for extra nodal AILD, colonic involvement can imitate the clinical and histologic features of inflammatory bowel disease.

Original languageEnglish (US)
Pages (from-to)2244-2250
Number of pages7
JournalCancer
Volume61
Issue number11
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Immunoblastic Lymphadenopathy
Inflammatory Bowel Diseases
Prednisone
Biopsy
Lymph Nodes
Sulfasalazine
Splenomegaly
Crohn Disease
Abdominal Pain
Hyperplasia
Gastrointestinal Tract
Diarrhea
Fever

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Rosenstein, Elliot D. ; Rickert, Robert R. ; Gutkin, Michael ; Bacay, Angelito ; Kramer, Neil. / Colonic involvement in angioimmunoblastic lymphadenopathy resembling inflammatory bowel disease. In: Cancer. 1988 ; Vol. 61, No. 11. pp. 2244-2250.
@article{a12c1fdd604449048f42b92c66fdbfab,
title = "Colonic involvement in angioimmunoblastic lymphadenopathy resembling inflammatory bowel disease",
abstract = "A woman 68 years of age had fever, malaise, diffuse lymphadenopathy, splenomegaly followed by abdominal pain, and diarrhea. A lymph node biopsy specimen showed nonspecific follicular hyperplasia. Symptoms were responsive initially to prednisone. Recurrent symptoms warranted colonic biopsy, which was consistent with Crohn's disease, and were responsive partially to prednisone and azulfidine. Because of progressive deterioration, a repeat lymph node biopsy was performed and showed the characteristic histologic feature of angioimmunoblastic lymphadenopathy (AILD). The evolution of the histopathologic features of the case is discussed, and gastrointestinal (GI) manifestations of AILD are reviewed. Although the GI tract is an unusual site for extra nodal AILD, colonic involvement can imitate the clinical and histologic features of inflammatory bowel disease.",
author = "Rosenstein, {Elliot D.} and Rickert, {Robert R.} and Michael Gutkin and Angelito Bacay and Neil Kramer",
year = "1988",
month = "1",
day = "1",
doi = "10.1002/1097-0142(19880601)61:11<2244::AID-CNCR2820611119>3.0.CO;2-G",
language = "English (US)",
volume = "61",
pages = "2244--2250",
journal = "Cancer",
issn = "0008-543X",
publisher = "John Wiley and Sons Inc.",
number = "11",

}

Colonic involvement in angioimmunoblastic lymphadenopathy resembling inflammatory bowel disease. / Rosenstein, Elliot D.; Rickert, Robert R.; Gutkin, Michael; Bacay, Angelito; Kramer, Neil.

In: Cancer, Vol. 61, No. 11, 01.01.1988, p. 2244-2250.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Colonic involvement in angioimmunoblastic lymphadenopathy resembling inflammatory bowel disease

AU - Rosenstein, Elliot D.

AU - Rickert, Robert R.

AU - Gutkin, Michael

AU - Bacay, Angelito

AU - Kramer, Neil

PY - 1988/1/1

Y1 - 1988/1/1

N2 - A woman 68 years of age had fever, malaise, diffuse lymphadenopathy, splenomegaly followed by abdominal pain, and diarrhea. A lymph node biopsy specimen showed nonspecific follicular hyperplasia. Symptoms were responsive initially to prednisone. Recurrent symptoms warranted colonic biopsy, which was consistent with Crohn's disease, and were responsive partially to prednisone and azulfidine. Because of progressive deterioration, a repeat lymph node biopsy was performed and showed the characteristic histologic feature of angioimmunoblastic lymphadenopathy (AILD). The evolution of the histopathologic features of the case is discussed, and gastrointestinal (GI) manifestations of AILD are reviewed. Although the GI tract is an unusual site for extra nodal AILD, colonic involvement can imitate the clinical and histologic features of inflammatory bowel disease.

AB - A woman 68 years of age had fever, malaise, diffuse lymphadenopathy, splenomegaly followed by abdominal pain, and diarrhea. A lymph node biopsy specimen showed nonspecific follicular hyperplasia. Symptoms were responsive initially to prednisone. Recurrent symptoms warranted colonic biopsy, which was consistent with Crohn's disease, and were responsive partially to prednisone and azulfidine. Because of progressive deterioration, a repeat lymph node biopsy was performed and showed the characteristic histologic feature of angioimmunoblastic lymphadenopathy (AILD). The evolution of the histopathologic features of the case is discussed, and gastrointestinal (GI) manifestations of AILD are reviewed. Although the GI tract is an unusual site for extra nodal AILD, colonic involvement can imitate the clinical and histologic features of inflammatory bowel disease.

UR - http://www.scopus.com/inward/record.url?scp=0023945871&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023945871&partnerID=8YFLogxK

U2 - 10.1002/1097-0142(19880601)61:11<2244::AID-CNCR2820611119>3.0.CO;2-G

DO - 10.1002/1097-0142(19880601)61:11<2244::AID-CNCR2820611119>3.0.CO;2-G

M3 - Article

C2 - 3365652

AN - SCOPUS:0023945871

VL - 61

SP - 2244

EP - 2250

JO - Cancer

JF - Cancer

SN - 0008-543X

IS - 11

ER -