Are Women With Threatened Preterm Labor More Dehydrated Than Women Without It?

Michael M. Aziz, Ankita Kulkarni, Oluwafisayo Tunde-Agbede, Carlos Benito, Yinka Oyelese

Research output: Contribution to journalArticle

Abstract

Objective: To determine if women who present to the labor and delivery unit at 23 0/7 to 36 6/7 weeks gestation with threatened preterm labor (TPTL) are more likely to be dehydrated than women who present at the same gestational age for other reasons. Design: Retrospective cohort study. Setting: An academic medical center in the northeastern United States. Participants: All women at preterm gestational ages 23 0/7 to 36 6/7 weeks who presented to the labor and delivery unit for care in 2014. Methods: We compared hydration status by urine specific gravity of women with TPTL to that of women with other chief complaints. Women for whom data were missing and those with hypertension, diabetes, renal disease, vaginal bleeding, ruptured membranes, advanced dilation (>3 cm), multiple gestation, or fetal demise were excluded. Chi-square statistic and a receiver operating characteristic (ROC) curve were used for data analysis. Results: A total of 840 women at 23 0/7 to 36 6/7 weeks gestation presented during the study period; 188 of these had TPTL, 261 had other chief complaints, and 391 were excluded. The proportion of women diagnosed with dehydration was similar between those with TPTL (39%) and those with other complaints (46%, p =.12). An ROC curve showed no association between TPTL and hydration status (area under the curve = 0.57, 95% confidence interval [0.46, 0.67]). Conclusion: At 23 0/7 to 36 6/7 weeks gestation, the hydration status of women with TPTL was not different from those without TPTL. Because there is no relationship, it is unlikely that hydration is a worthwhile therapy for women with TPTL, although additional prospective study is warranted.

Original languageEnglish (US)
Pages (from-to)602-607
Number of pages6
JournalJOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing
Volume47
Issue number5
DOIs
StatePublished - Sep 1 2018

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Premature Obstetric Labor
Pregnancy
ROC Curve
Gestational Age
Women's Rights
New England
Specific Gravity
Renal Hypertension
Fetal Death
Uterine Hemorrhage
Dehydration
Area Under Curve
Dilatation
Cohort Studies
Retrospective Studies
Urine
Prospective Studies
Confidence Intervals
Membranes

All Science Journal Classification (ASJC) codes

  • Pediatrics
  • Critical Care
  • Maternity and Midwifery

Cite this

Aziz, Michael M. ; Kulkarni, Ankita ; Tunde-Agbede, Oluwafisayo ; Benito, Carlos ; Oyelese, Yinka. / Are Women With Threatened Preterm Labor More Dehydrated Than Women Without It?. In: JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing. 2018 ; Vol. 47, No. 5. pp. 602-607.
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abstract = "Objective: To determine if women who present to the labor and delivery unit at 23 0/7 to 36 6/7 weeks gestation with threatened preterm labor (TPTL) are more likely to be dehydrated than women who present at the same gestational age for other reasons. Design: Retrospective cohort study. Setting: An academic medical center in the northeastern United States. Participants: All women at preterm gestational ages 23 0/7 to 36 6/7 weeks who presented to the labor and delivery unit for care in 2014. Methods: We compared hydration status by urine specific gravity of women with TPTL to that of women with other chief complaints. Women for whom data were missing and those with hypertension, diabetes, renal disease, vaginal bleeding, ruptured membranes, advanced dilation (>3 cm), multiple gestation, or fetal demise were excluded. Chi-square statistic and a receiver operating characteristic (ROC) curve were used for data analysis. Results: A total of 840 women at 23 0/7 to 36 6/7 weeks gestation presented during the study period; 188 of these had TPTL, 261 had other chief complaints, and 391 were excluded. The proportion of women diagnosed with dehydration was similar between those with TPTL (39{\%}) and those with other complaints (46{\%}, p =.12). An ROC curve showed no association between TPTL and hydration status (area under the curve = 0.57, 95{\%} confidence interval [0.46, 0.67]). Conclusion: At 23 0/7 to 36 6/7 weeks gestation, the hydration status of women with TPTL was not different from those without TPTL. Because there is no relationship, it is unlikely that hydration is a worthwhile therapy for women with TPTL, although additional prospective study is warranted.",
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Are Women With Threatened Preterm Labor More Dehydrated Than Women Without It? / Aziz, Michael M.; Kulkarni, Ankita; Tunde-Agbede, Oluwafisayo; Benito, Carlos; Oyelese, Yinka.

In: JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing, Vol. 47, No. 5, 01.09.2018, p. 602-607.

Research output: Contribution to journalArticle

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AU - Benito, Carlos

AU - Oyelese, Yinka

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