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Research Output 1987 2019

2019

Real-world experience with pembrolizumab in patients with advanced melanoma: A large retrospective observational study

Liu, F. X., Ou, W., Diede, S. J. & Whitman, E., Jul 1 2019, In : Medicine. 98, 30, p. e16542

Research output: Contribution to journalArticle

Open Access
Observational Studies
Melanoma
Retrospective Studies
Survival
Adrenal Cortex Hormones
2 Citations (Scopus)

Treatment patterns and outcomes for patients with advanced melanoma in US oncology clinical practices

Whitman, E., Liu, F. X., Cao, X., Diede, S. J., Haiderali, A. & Abernethy, A. P., Feb 1 2019, In : Future Oncology. 15, 5, p. 459-471 13 p.

Research output: Contribution to journalArticle

Medical Oncology
Melanoma
Electronic Health Records
Mitogen-Activated Protein Kinase Kinases
Observational Studies
2018
28 Citations (Scopus)
Melanoma
Placebos
Mutation
Disease-Free Survival
Keratoacanthoma
12 Citations (Scopus)

An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: Version 2.0

Sullivan, R. J., Atkins, M. B., Kirkwood, J. M., Agarwala, S. S., Clark, J. I., Ernstoff, M. S., Fecher, L., Gajewski, T. F., Gastman, B., Lawson, D. H., Lutzky, J., McDermott, D. F., Margolin, K. A., Mehnert, J. M., Pavlick, A. C., Richards, J. M., Rubin, K. M., Sharfman, W., Silverstein, S., Slingluff, C. L. & 8 others, Sondak, V. K., Tarhini, A. A., Thompson, J. A., Urba, W. J., White, R. L., Whitman, E., Hodi, F. S. & Kaufman, H. L., May 30 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 44.

Research output: Contribution to journalArticle

Immunotherapy
Melanoma
Consensus
Skin
Advisory Committees
9 Citations (Scopus)

Phase IIIb safety results from an expanded-access protocol of talimogene laherparepvec for patients with unresected, stage IIIB-IVM1c melanoma

Chesney, J., Awasthi, S., Curti, B., Hutchins, L., Linette, G., Triozzi, P., Tan, M. C. B., Brown, R. E., Nemunaitis, J., Whitman, E., Windham, C., Lutzky, J., Downey, G. F., Batty, N. & Amatruda, T., Jan 1 2018, In : Melanoma Research. 28, 1, p. 44-51 8 p.

Research output: Contribution to journalArticle

Melanoma
Safety
Therapeutics
Hyperhidrosis
Drug Approval
2017
3 Citations (Scopus)

Vemurafenib treatment for patients with locally advanced, unresectable stage IIIC or metastatic melanoma and activating exon 15 BRAF mutations other than V600E

Hallmeyer, S., Gonzalez, R., Lawson, D. H., Cranmer, L. D., Linette, G. P., Puzanov, I., Taback, B., Cowey, C. L., Ribas, A., Daniels, G. A., Moore, T., Gibney, G. T., Tawbi, H., Whitman, E., Lee, G., Mun, Y., Liu, S. & Hamid, O., Jan 1 2017, In : Melanoma Research. 27, 6, p. 585-590 6 p.

Research output: Contribution to journalArticle

Exons
Melanoma
Mutation
Therapeutics
Confidence Intervals
2016
28 Citations (Scopus)

Results of a Randomized Controlled Multicenter Phase III Trial of Percutaneous Hepatic Perfusion Compared with Best Available Care for Patients with Melanoma Liver Metastases

Hughes, M. S., Zager, J., Faries, M., Alexander, H. R., Royal, R. E., Wood, B., Choi, J., McCluskey, K., Whitman, E., Agarwala, S., Siskin, G., Nutting, C., Toomey, M. A., Webb, C., Beresnev, T. & Pingpank, J. F., Apr 1 2016, In : Annals of Surgical Oncology. 23, 4, p. 1309-1319 11 p.

Research output: Contribution to journalArticle

Melanoma
Patient Care
Melphalan
Perfusion
Neoplasm Metastasis
41 Citations (Scopus)

Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study

Kaufman, H. L., Amatruda, T., Reid, T., Gonzalez, R., Glaspy, J., Whitman, E., Harrington, K., Nemunaitis, J., Zloza, A., Wolf, M. & Senzer, N. N., Mar 15 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 12.

Research output: Contribution to journalArticle

Melanoma
Phase II Clinical Trials
Neoplasms
Oncolytic Viruses
Granulocyte-Macrophage Colony-Stimulating Factor
2012
12 Citations (Scopus)

Role of sentinel lymphadenectomy in thin cutaneous melanomas with positive deep margins on initial biopsy

Koshenkov, V. P., Shulkin, D., Bustami, R., Chevinsky, A. H. & Whitman, E., Sep 15 2012, In : Journal of Surgical Oncology. 106, 4, p. 363-368 6 p.

Research output: Contribution to journalArticle

Lymph Node Excision
Melanoma
Biopsy
Sentinel Lymph Node Biopsy
Skin
2011
98 Citations (Scopus)

A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma

Lewis, K. D., Samlowski, W., Ward, J., Catlett, J., Cranmer, L., Kirkwood, J., Lawson, D., Whitman, E. & Gonzalez, R., Feb 1 2011, In : Investigational New Drugs. 29, 1, p. 161-166 6 p.

Research output: Contribution to journalArticle

Melanoma
Inhibitor of Apoptosis Proteins
Melanocytes
Arthralgia
Back Pain
53 Citations (Scopus)

Factors predictive of the status of sentinel lymph nodes in melanoma patients from a large multicenter database

White, R. L. R., Ayers, G. D., Stell, V. H., Ding, S., Gershenwald, J. E., Salo, J. C., Pockaj, B. A., Essner, R., Faries, M., Charney, K. J., Avisar, E., Hauschild, A., Egberts, F., Averbook, B. J., Garberoglio, C. A., Vetto, J. T., Ross, M. I., Chu, D., Trisal, V., Hoekstra, H. & 11 others, Whitman, E., Wanebo, H. J., Debonis, D., Vezeridis, M., Chevinsky, A., Kashani-Sabet, M., Shyr, Y., Berry, L., Zhao, Z., Soong, S. J. & Leong, S. P. L., Dec 1 2011, In : Annals of Surgical Oncology. 18, 13, p. 3593-3600 8 p.

Research output: Contribution to journalArticle

Sentinel Lymph Node Biopsy
Melanoma
Databases
Multivariate Analysis
Neoplasms
559 Citations (Scopus)

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

Schwartzentruber, D. J., Lawson, D. H., Richards, J. M., Conry, R. M., Miller, D. M., Treisman, J., Gailani, F., Riley, L., Conlon, K., Pockaj, B., Kendra, K. L., White, R. L., Gonzalez, R., Kuzel, T. M., Curti, B., Leming, P. D., Whitman, E., Balkissoon, J., Reintgen, D. S., Kaufman, H. & 6 others, Marincola, F. M., Merino, M. J., Rosenberg, S. A., Choyke, P., Vena, D. & Hwu, P., Jun 2 2011, In : New England Journal of Medicine. 364, 22, p. 2119-2127 9 p.

Research output: Contribution to journalArticle

Subunit Vaccines
Interleukin-2
Melanoma
Vaccines
Confidence Intervals
2010
63 Citations (Scopus)

A phase 2 study of high-dose Allovectin-7 in patients with advanced metastatic melanoma

Bedikian, A. Y., Richards, J., Kharkevitch, D., Atkins, M. B., Whitman, E. & Gonzalez, R., Jun 1 2010, In : Melanoma Research. 20, 3, p. 218-226 9 p.

Research output: Contribution to journalArticle

Melanoma
Confidence Intervals
Intralesional Injections
Allovectin-7
Histocompatibility Antigens Class I
2009
35 Citations (Scopus)

Molecular classification of melanomas and nevi using gene expression microarray signatures and formalin-fixed and paraffin-embedded tissue

Koh, S. S., Opel, M. L., Wei, J. P. J., Yau, K., Shah, R., Gorre, M. E., Whitman, E., Shitabata, P. K., Tao, Y., Cochran, A. J., Abrishami, P. & Binder, S. W., Apr 1 2009, In : Modern Pathology. 22, 4, p. 538-546 9 p.

Research output: Contribution to journalArticle

Nevi and Melanomas
Transcriptome
Paraffin
Formaldehyde
Oligonucleotide Array Sequence Analysis
378 Citations (Scopus)

Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma

Senzer, N. N., Kaufman, H. L., Amatruda, T., Nemunaitis, M., Reid, T., Daniels, G., Gonzalez, R., Glaspy, J., Whitman, E., Harrington, K., Goldsweig, H., Marshall, T., Love, C., Coffin, R. & Nemunaitis, J. J., Dec 1 2009, In : Journal of Clinical Oncology. 27, 34, p. 5763-5771 9 p.

Research output: Contribution to journalArticle

Phase II Clinical Trials
Herpesviridae
Granulocyte-Macrophage Colony-Stimulating Factor
Melanoma
temozolomide
2008
184 Citations (Scopus)

Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: The C-100-21 study group

Testori, A., Richards, J., Whitman, E., Mann, G. B., Lutzky, J., Camacho, L., Parmiani, G., Tosti, G., Kirkwood, J. M., Hoos, A., Yuh, L., Gupta, R. & Srivastava, P. K., Feb 20 2008, In : Journal of Clinical Oncology. 26, 6, p. 955-962 8 p.

Research output: Contribution to journalArticle

Subunit Vaccines
Heat-Shock Proteins
Melanoma
Physicians
Neoplasms
2007
65 Citations (Scopus)

Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon alfa-2b compared with high-dose interferon alfa-2b for resected stage III cutaneous melanoma

Mitchell, M. S., Abrams, J., Thompson, J. A., Kashani-Sabet, M., DeConti, R. C., Hwu, W. J., Atkins, M. B., Whitman, E., Ernstoff, M. S., Haluska, F. G., Jakowatz, J. G., Das Gupta, T. K., Richards, J. M., Samlowski, W. E., Costanzi, J. J., Aronson, F. R., Deisseroth, A. B., Dudek, A. Z. & Jones, V. E., May 20 2007, In : Journal of Clinical Oncology. 25, 15, p. 2078-2085 8 p.

Research output: Contribution to journalArticle

interferon alfa-2b
Melanoma
Vaccines
Active Immunotherapy
Skin
2006

Us counterpoint to chapter 21

Whitman, E., Dec 1 2006, The Bionic Human: Health Promotion for People With Implanted Prosthetic Devices. Humana Press, p. 588-592 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2003
1 Citation (Scopus)

Surgical margins in melanoma

Whitman, E., Feb 1 2003, In : Facial Plastic Surgery Clinics of North America. 11, 1, p. 87-91 5 p.

Research output: Contribution to journalArticle

Melanoma
Clinical Trials
Survival
Margins of Excision
Therapeutics
2002
13 Citations (Scopus)

Pharmacokinetics of histamine dihydrochloride in healthy volunteers and cancer patients: Implications for combined immunotherapy with interleukin-2

Middleton, M., Sarno, M., Agarwala, S. S., Glaspy, J., Laurent, A., McMasters, K., Naredi, P., O'Day, S., Whitman, E., Danson, S., Cosford, R. & Gehlsen, K., Jul 2 2002, In : Journal of Clinical Pharmacology. 42, 7, p. 774-781 8 p.

Research output: Contribution to journalArticle

Immunotherapy
Histamine
Interleukin-2
Healthy Volunteers
Pharmacokinetics
141 Citations (Scopus)

Results from a randomized phase III study comparing combined treatment with histamine dihydrochloride plus interleukin-2 versus interleukin-2 alone in patients with metastatic melanoma

Agarwala, S. S., Glaspy, J., O'Day, S. J., Mitchell, M., Gutheil, J., Whitman, E., Gonzalez, R., Hersh, E., Feun, L., Belt, R., Meyskens, F., Hellstrand, K., Wood, D., Kirkwood, J. M., Gehlsen, K. R. & Naredi, P., Jan 1 2002, In : Journal of Clinical Oncology. 20, 1, p. 125-133 9 p.

Research output: Contribution to journalArticle

Histamine
Interleukin-2
Melanoma
Survival
Therapeutics
1996
154 Citations (Scopus)

Comparative analysis of laparoscopic versus open splenectomy

Brunt, L. M., Langer, J. C., Quasebarth, M. A. & Whitman, E., Nov 1 1996, In : American Journal of Surgery. 172, 5, p. 596-601 6 p.

Research output: Contribution to journalArticle

Splenectomy
Operative Time
Spleen
Anesthesiology
69 Citations (Scopus)

Complications associated with the use of central venous access devices

Whitman, E., Jan 1 1996, In : Current Problems in Surgery. 33, 4, p. 309-378 70 p.

Research output: Contribution to journalArticle

Prosthesis-Related Infections
Central Venous Catheterization
Equipment Failure
Indwelling Catheters
Thrombosis
1995

A Letter from the Editor

Whitman, E., Jan 1 1995, In : Journal of Vascular Access Devices. 1, 1, 1 p.

Research output: Contribution to journalLetter

A Letter from the Editor

Whitman, E., Jan 1 1995, In : Journal of Vascular Access Devices. 1, 2, 1 p.

Research output: Contribution to journalLetter

24 Citations (Scopus)

Comparison of diagnostic specimens and methods to evaluate infected venous access ports

Whitman, E. & Boatman, A. M., Jan 1 1995, In : The American Journal of Surgery. 170, 6, p. 665-670 6 p.

Research output: Contribution to journalArticle

Infection
Device Removal
Catheters
19 Citations (Scopus)

Construction and expression in tumor cells of a recombinant vaccinia virus encoding human interleukin-1β

Peplinski, G. R., Tsung, K., Whitman, E., Meko, J. B. & Norton, J. A., Mar 1 1995, In : Annals of Surgical Oncology. 2, 2, p. 151-159 9 p.

Research output: Contribution to journalArticle

Vaccinia virus
Interleukin-1
Neoplasms
Cytokines
Homologous Recombination
1 Citation (Scopus)

Editorial: A Critical Evaluation of Valved Central Venous Catheters

Whitman, E., Jan 1 1995, In : Journal of Vascular Access Devices. 1, 2, p. 11-12 2 p.

Research output: Contribution to journalEditorial

Letter from the Editor

Whitman, E., Jan 1 1995, In : Journal of Vascular Access Devices. 1, 3, 1 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Outcome Analysis for Vascular Access Devices: System Development

Whitman, E., Jan 1 1995, In : Journal of Vascular Access Devices. 1, 1, p. 11-15 5 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Venographic surveillance of tunneled venous access devices in adult oncology patients

Horne, M. K., May, D. J., Alexander, H. R., Steinhaus, E. P., Whitman, E., Chang, R. C. & Doppman, J. L., Mar 1 1995, In : Annals of Surgical Oncology. 2, 2, p. 174-178 5 p.

Research output: Contribution to journalArticle

Equipment and Supplies
Catheterization
Thrombosis
Axillary Vein
Subclavian Vein
1994
27 Citations (Scopus)

Endocrine surgical diseases of elderly patients

Whitman, E. & Norton, J. A., Jan 1 1994, In : Surgical Clinics of North America. 74, 1, p. 127-144 18 p.

Research output: Contribution to journalReview article

Endocrine System Diseases
Postoperative Care
Thyroid Nodule
Primary Hyperparathyroidism
Thyroid Neoplasms
13 Citations (Scopus)

Experimental gene therapy of human colon cancer

Bold, R. J., Warren, R. E., Ishizuka, J., Cho-Chung, Y. S., Townsend, C. M., Thompson, J. C., Joehl, R. J. & Whitman, E., Jan 1 1994, In : Surgery. 116, 2, p. 189-196 8 p.

Research output: Contribution to journalArticle

Investigational Therapies
Genetic Therapy
Colonic Neoplasms
Oligodeoxyribonucleotides
Cyclic AMP
36 Citations (Scopus)

In vitro and in vivo kinetics of recombinant vaccinia virus cancer-gene therapy

Whitman, E., Tsung, K., Paxson, J., Norton, J. A., Shaked, A. & Lyerly, H. K., Jan 1 1994, In : Surgery. 116, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

Vaccinia virus
Neoplasm Genes
Genetic Therapy
Neoplasms
Interleukin-2
7 Citations (Scopus)

Retained Hickman catheter cuff as an infection source following allogeneic bone marrow transplant

Ruppel, L. J., Brown, R. A., Borson, R. A. & Whitman, E., Jan 1 1994, In : Bone Marrow Transplantation. 14, 1, p. 169-171 3 p.

Research output: Contribution to journalArticle

Catheters
Bone Marrow
Graft vs Host Disease
Transplants
Infection
12 Citations (Scopus)

Upper extremity impedance plethysmography in patients with venous access devices

Horne, M. K., Mayo, D. J., Alexander, H. R., Steinhaus, E. P., Chang, R. C., Whitman, E. & Gralnick, H. R., Jan 1 1994, In : Thrombosis and Haemostasis. 72, 4, p. 540-542 3 p.

Research output: Contribution to journalArticle

Impedance Plethysmography
Upper Extremity
Equipment and Supplies
Phlebography
Population
4 Citations (Scopus)

Vascular Access for Therapeutic Plasma Exchange

Grishaber, J. E. & Whitman, E., Jan 1 1994, In : Artificial Organs. 18, 4, p. 305-308 4 p.

Research output: Contribution to journalArticle

Vascular Access Devices
Plasma Exchange
Blood Vessels
Plasmas
Catheters
1993
10 Citations (Scopus)

Insulinoma

Norton, J. A. & Whitman, E., Jan 1 1993, In : Endocrinologist. 3, 4, p. 258-267 10 p.

Research output: Contribution to journalArticle

Insulinoma
Multiple Endocrine Neoplasia Type 1
Neoplasms
Hypoglycemia
Pancreas
1988

Velocity spectral analysis in the classification of lower extremity arterial occlusive disease.

Whitman, E., Neumyer, M. M., Atnip, R. G. & Thiele, B. L., Sep 1 1988, In : Current Surgery. 45, 5, p. 383-386 4 p.

Research output: Contribution to journalArticle

Intermittent Claudication
Arterial Occlusive Diseases
Blood Flow Velocity
Femoral Artery
Lower Extremity
1987
65 Citations (Scopus)

A persistent outbreak of measles despite appropriate prevention and control measures

Davis, R. M., Whitman, E., Orenstein, W. A., Preblud, S. R., Markowitz, L. E. & Hinman, A. R., Jan 1 1987, In : American Journal of Epidemiology. 126, 3, p. 438-449 12 p.

Research output: Contribution to journalArticle

Measles
Disease Outbreaks
Vaccination
Vaccines
Students