Research Output 1981 2019

2019
1 Citation (Scopus)

Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

Haberman, Y., Schirmer, M., Dexheimer, P. J., Karns, R., Braun, T., Kim, M. O., Walters, T. D., Baldassano, R. N., Noe, J. D., Rosh, J., Markowitz, J., Crandall, W. V., Mack, D. R., Griffiths, A. M., Heyman, M. B., Baker, S. S., Kellermayer, R., Moulton, D., Patel, A. S., Gulati, A. S. & 18 others, Steiner, S. J., LeLeiko, N., Otley, A., Oliva-Hemker, M., Ziring, D., Kirschner, B. S., Keljo, D. J., Guthery, S. L., Cohen, S. A., Snapper, S., Evans, J., Dubinsky, M., Aronow, B., Hyams, J. S., Kugathasan, S., Huttenhower, C., Xavier, R. J. & Denson, L. A., Mar 1 2019, In : Mucosal Immunology. 12, 2, p. 491-502 12 p.

Research output: Contribution to journalArticle

alpha-Defensins
Dysbiosis
Defensins
Paneth Cells
Peyer's Patches

Biologics and surgery in inflammatory bowel disease: Learning at the cutting edge

Rosh, J., Mar 1 2019, In : Journal of pediatric gastroenterology and nutrition. 68, 3, p. 297-298 2 p.

Research output: Contribution to journalComment/debate

Biological Products
Inflammatory Bowel Diseases
Learning
3 Citations (Scopus)

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation

Somineni, H. K., Venkateswaran, S., Kilaru, V., Marigorta, U. M., Mo, A., Okou, D. T., Kellermayer, R., Mondal, K., Cobb, D., Walters, T. D., Griffiths, A., Noe, J. D., Crandall, W. V., Rosh, J., Mack, D. R., Heyman, M. B., Baker, S. S., Stephens, M. C., Baldassano, R. N., Markowitz, J. F. & 9 others, Dubinsky, M. C., Cho, J., Hyams, J. S., Denson, L. A., Gibson, G., Cutler, D. J., Conneely, K. N., Smith, A. K. & Kugathasan, S., Jun 1 2019, In : Gastroenterology. 156, 8, p. 2254-2265.e3

Research output: Contribution to journalArticle

Open Access
DNA Methylation
Crohn Disease
Inflammation
Methylation
Disease Progression
5 Citations (Scopus)

Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study

Hyams, J. S., Davis Thomas, S., Gotman, N., Haberman, Y., Karns, R., Schirmer, M., Mo, A., Mack, D. R., Boyle, B., Griffiths, A. M., LeLeiko, N. S., Sauer, C. G., Keljo, D. J., Markowitz, J., Baker, S. S., Rosh, J., Baldassano, R. N., Patel, A., Pfefferkorn, M., Otley, A. & 30 others, Heyman, M., Noe, J., Oliva-Hemker, M., Rufo, P. A., Strople, J., Ziring, D., Guthery, S. L., Sudel, B., Benkov, K., Wali, P., Moulton, D., Evans, J., Kappelman, M. D., Marquis, M. A., Sylvester, F. A., Collins, M. H., Venkateswaran, S., Dubinsky, M., Tangpricha, V., Spada, K. L., Saul, B., Wang, J., Serrano, J., Hommel, K., Marigorta, U. M., Gibson, G., Xavier, R. J., Kugathasan, S., Walters, T. & Denson, L. A., Apr 27 2019, In : The Lancet. 393, 10182, p. 1708-1720 13 p.

Research output: Contribution to journalArticle

Colitis
Cohort Studies
Pediatrics
Mesalamine
Adrenal Cortex Hormones

Obtaining Vitamin D Levels in Children With Fractures Improves Supplementation Compliance

AHS Bone Health Compliance Group, Jul 1 2019, In : Journal of Pediatric Orthopaedics. 39, 6, p. E436-E440

Research output: Contribution to journalArticle

Vitamin D
Compliance
Abbreviated Injury Scale
Caregivers
Odds Ratio
2 Citations (Scopus)

Pediatric inflammatory bowel disease clinical innovations meeting of the Crohn's and colitis foundation: Charting the future of pediatric IBD

Picoraro, J. A., Lee, D., Heller, C. A., Weaver, A., Hyams, J. S., Conklin, L. S., Otley, A., Ziring, D., Kugathasan, S., Rosh, J., Mulberg, A., Denson, L. A., Kappelman, M. D., Grossman, A. B., Bousvaros, A. & Park, K. T., Jan 1 2019, In : Inflammatory bowel diseases. 25, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

Colitis
Inflammatory Bowel Diseases
Pediatrics
Research
Intestinal Diseases

Prudence Using Serology to Determine Vaccine-Induced Immunity to Measles and Varicella in Patients With Inflammatory Bowel Disease

Caldera, F., Farraye, F. A., Rosh, J. & Hayney, M. S., Aug 20 2019, In : Inflammatory bowel diseases. 25, 9, p. e113

Research output: Contribution to journalArticle

Chickenpox
Measles
Serology
Inflammatory Bowel Diseases
Immunity

Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes

Grace, R. F., Shimano, K. A., Bhat, R., Neunert, C., Bussel, J. B., Klaassen, R. J., Lambert, M. P., Rothman, J. A., Breakey, V. R., Hege, K., Bennett, C. M., Rose, M. J., Haley, K. M., Buchanan, G. R., Geddis, A., Lorenzana, A., Jeng, M., Pastore, Y. D., Crary, S. E., Neier, M. & 4 others, Neufeld, E. J., Neu, N., Forbes, P. W. & Despotovic, J. M., Jul 1 2019, In : American Journal of Hematology. 94, 7, p. 741-750 10 p.

Research output: Contribution to journalArticle

Open Access
Idiopathic Thrombocytopenic Purpura
Platelet Count
Hemorrhage
Quality of Life
Therapeutics

Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease

Wu, J., Lubman, D. M., Kugathasan, S., Denson, L. A., Hyams, J. S., Dubinsky, M. C., Griffiths, A. M., Baldassano, R. N., Noe, J. D., Rabizadeh, S., Gulati, A. S., Rosh, J., Crandall, W. V., Higgins, P. D. R. & Stidham, R. W., May 1 2019, In : The American journal of gastroenterology. 114, 5, p. 777-785 9 p.

Research output: Contribution to journalArticle

Crohn Disease
Blood Proteins
Extracellular Matrix Proteins
Fibrosis
Biomarkers
1 Citation (Scopus)

The effects of concomitant immunomodulators on the pharmacokinetics, efficacy and safety of adalimumab in paediatric patients with Crohn’s disease: a post hoc analysis

Hyams, J. S., Dubinsky, M., Rosh, J., Ruemmele, F. M., Eichner, S. F., Maa, J. F., Lazar, A., Alperovich, G., Mostafa, N. M. & Robinson, A. M., Jan 1 2019, In : Alimentary Pharmacology and Therapeutics. 49, 2, p. 155-164 10 p.

Research output: Contribution to journalArticle

Immunologic Factors
Crohn Disease
Pharmacokinetics
Pediatrics
Safety
5 Citations (Scopus)

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

Haberman, Y., Karns, R., Dexheimer, P. J., Schirmer, M., Somekh, J., Jurickova, I., Braun, T., Novak, E., Bauman, L., Collins, M. H., Mo, A., Rosen, M. J., Bonkowski, E., Gotman, N., Marquis, A., Nistel, M., Rufo, P. A., Baker, S. S., Sauer, C. G., Markowitz, J. & 22 others, Pfefferkorn, M. D., Rosh, J., Boyle, B. M., Mack, D. R., Baldassano, R. N., Shah, S., Leleiko, N. S., Heyman, M. B., Grifiths, A. M., Patel, A. S., Noe, J. D., Aronow, B. J., Kugathasan, S., Walters, T. D., Gibson, G., Thomas, S. D., Mollen, K., Shen-Orr, S., Huttenhower, C., Xavier, R. J., Hyams, J. S. & Denson, L. A., Dec 1 2019, In : Nature Communications. 10, 1, 38.

Research output: Contribution to journalArticle

Open Access
Ulcerative Colitis
Transcriptome
genes
Genes
therapy

Unmasking Hemophilia B after Hip Aspiration: A Case Report

Minkowitz, B., Lillie, E., Ristic, J. R. & Gregory, J. J., Apr 1 2019, In : JBJS Case Connector. 9, 2, e0275.

Research output: Contribution to journalArticle

Hemophilia B
Hip
Factor IX
Pain
Magnetic Resonance Imaging

Y chromosome gene copy number and lack of autism phenotype in a male with an isodicentric Y chromosome and absent NLGN4Y expression

Ross, J. L., Bloy, L., Roberts, T. P. L., Miller, J., Xing, C., Silverman, L. & Zinn, A. R., Oct 1 2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 7, p. 471-482 12 p.

Research output: Contribution to journalArticle

Y-Linked Genes
Gene Dosage
Y Chromosome
Autistic Disorder
Phenotype
2018
8 Citations (Scopus)

Biologics Delay Progression of Crohn's Disease, but Not Early Surgery, in Children

Kerur, B., Machan, J. T., Shapiro, J. M., Cerezo, C. S., Markowitz, J., Mack, D. R., Griffiths, A. M., Otley, A. R., Pfefferkorn, M. D., Rosh, J., Keljo, D. J., Boyle, B., Oliva-Hemker, M., Kay, M. H., Saeed, S. A., Grossman, A. B., Sudel, B., Kappelman, M. D., Schaefer, M., Tomer, G. & 4 others, Bousvaros, A., Lerer, T., Hyams, J. S. & LeLeiko, N. S., Sep 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 9, p. 1467-1473 7 p.

Research output: Contribution to journalArticle

Biological Products
Crohn Disease
Disease Progression
Pediatrics
Registries
8 Citations (Scopus)

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

Schirmer, M., Denson, L., Vlamakis, H., Franzosa, E. A., Thomas, S., Gotman, N. M., Rufo, P., Baker, S. S., Sauer, C., Markowitz, J., Pfefferkorn, M., Oliva-Hemker, M., Rosh, J., Otley, A., Boyle, B., Mack, D., Baldassano, R., Keljo, D., LeLeiko, N., Heyman, M. & 8 others, Griffiths, A., Patel, A. S., Noe, J., Kugathasan, S., Walters, T., Huttenhower, C., Hyams, J. & Xavier, R. J., Oct 10 2018, In : Cell Host and Microbe. 24, 4, p. 600-610.e4

Research output: Contribution to journalArticle

Ulcerative Colitis
Therapeutics
Colectomy
Gastrointestinal Microbiome
Pediatric ulcerative colitis
2 Citations (Scopus)

Efficacy of adalimumab for treatment of perianal fistula in children with moderately to severely active Crohn's disease: Results from imagine 1 and imagine 2

Ruemmele, F. M., Rosh, J., Faubion, W. A., Dubinsky, M. C., Turner, D., Lazar, A., Eichner, S., Maa, J. F., Alperovich, G., Robinson, A. M. & Hyams, J. S., Jan 1 2018, In : Journal of Crohn's and Colitis. 12, 10, p. 1249-1254 6 p.

Research output: Contribution to journalArticle

Crohn Disease
Fistula
Safety
Adalimumab
Placebos
2 Citations (Scopus)

Evolution of pediatric inflammatory bowel disease unclassified (IBD-U): Incorporated with serological and gene expression profiles

Chandradevan, R., Hofmekler, T., Mondal, K., Harun, N., Venkateswaran, S., Somineni, H. K., Ballengee, C. R., Kim, M. O., Griffiths, A., Noe, J. D., Crandall, W. V., Snapper, S., Rabizadeh, S., Rosh, J., Walters, T. D., Bertha, M., Dubinsky, M. C., Denson, L. A., Sauer, C. G., Markowitz, J. F. & 3 others, LeLeiko, N. S., Hyams, J. S. & Kugathasan, S., Oct 1 2018, In : Inflammatory bowel diseases. 24, 10, p. 2285-2290 6 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Transcriptome
Pediatrics
Ulcerative Colitis
Crohn Disease
5 Citations (Scopus)

Free and bioavailable 25-hydroxyvitamin D concentrations are associated with disease activity in pediatric patients with newly diagnosed treatment naive ulcerative colitis

Sauer, C. G., Loop, M. S., Venkateswaran, S., Tangpricha, V., Ziegler, T. R., Dhawan, A., McCall, C., Bonkowski, E., Mack, D. R., Boyle, B., Griffiths, A. M., Leleiko, N. S., Keljo, D. J., Markowitz, J., Baker, S. S., Rosh, J., Baldassano, R. N., Davis, S., Patel, S., Wang, J. & 6 others, Marquis, A., Spada, K. L., Kugathasan, S., Walters, T., Hyams, J. S. & Denson, L. A., Feb 16 2018, In : Inflammatory bowel diseases. 24, 3, p. 641-650 10 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Vitamin D
Pediatrics
Colitis
Leukocyte L1 Antigen Complex

IBD LIVE Case Series: Case 9: Do Race and Extraintestinal Manifestations Affect Treatment of Severe Crohn's Colitis?

Proksell, S. S., Greer, J. B., Theisen, B. K., Davis, P. L., Rosh, J., Keljo, D. J., Goyal, A., Shah, S. A., Brand, M. H., Herfarth, H. H., Cross, R. K., Siegel, C. A., Koltun, W. A., Isaacs, K. L. & Regueiro, M. D., Mar 19 2018, In : Inflammatory bowel diseases. 24, 4, p. 698-713 16 p.

Research output: Contribution to journalArticle

Colitis
Therapeutics
9 Citations (Scopus)

Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease

Haberman, Y., Benshoshan, M., Di Segni, A., Dexheimer, P. J., Braun, T., Weiss, B., Walters, T. D., Baldassano, R. N., Noe, J. D., Markowitz, J., Rosh, J., Heyman, M. B., Griffiths, A. M., Crandall, W. V., Mack, D. R., Baker, S. S., Kellermayer, R., Patel, A., Otley, A., Steiner, S. J. & 17 others, Gulati, A. S., Guthery, S. L., Leleiko, N., Moulton, D., Kirschner, B. S., Snapper, S., Avivi, C., Barshack, I., Oliva-Hemker, M., Cohen, S. A., Keljo, D. J., Ziring, D., Anikster, Y., Aronow, B., Hyams, J. S., Kugathasan, S. & Denson, L. A., Jan 18 2018, In : Inflammatory bowel diseases. 24, 2, p. 346-360 15 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Ileum
Crohn Disease
Therapeutics
Interleukin-1
7 Citations (Scopus)

Physician decision making in selection of second-line treatments in immune thrombocytopenia in children

Grace, R. F., Despotovic, J. M., Bennett, C. M., Bussel, J. B., Neier, M., Neunert, C., Crary, S. E., Pastore, Y. D., Klaassen, R. J., Rothman, J. A., Hege, K., Breakey, V. R., Rose, M. J., Shimano, K. A., Buchanan, G. R., Geddis, A., Haley, K. M., Lorenzana, A., Thompson, A., Jeng, M. & 4 others, Neufeld, E. J., Brown, T., Forbes, P. W. & Lambert, M. P., Jul 1 2018, In : American Journal of Hematology. 93, 7, p. 882-888 7 p.

Research output: Contribution to journalArticle

Idiopathic Thrombocytopenic Purpura
Decision Making
Physicians
Patient Preference
Therapeutics

Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children

Spencer, E. A., Davis, S. M., Mack, D. R., Boyle, B. M., Griffiths, A. M., Leleiko, N. S., Sauer, C. G., Keljo, D. J., Markowitz, J. F., Baker, S. S., Rosh, J., Baldassano, R. N., Oliva-Hemker, M., Pfefferkorn, M. D., Otley, A. R., Heyman, M. B., Noe, J. D., Patel, A. S., Rufo, P. A., Benkov, K. & 16 others, Evans, J., Guthery, S., Kappelman, M., Moulton, D., Strople, J., Sudel, B., Wali, P., Ziring, D., Tangpricha, V., Marquis, M. A., Walters, T. D., Collins, M. H., Kugathasan, S., Denson, L. A., Hyams, J. S. & Dubinsky, M. C., May 18 2018, In : Inflammatory bowel diseases. 24, 6, p. 1335-1343 9 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Serology
Phenotype
Microbial Interactions
Leukocyte L1 Antigen Complex
5 Citations (Scopus)

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn’s Disease in Children

Lindoso, L., Mondal, K., Venkateswaran, S., Somineni, H. K., Ballengee, C., Walters, T. D., Griffiths, A., Noe, J. D., Crandall, W., Snapper, S., Rabizadeh, S., Rosh, J., LeLeiko, N., Guthery, S., Mack, D., Kellermayer, R., Gulati, A. S., Pfefferkorn, M. D., Moulton, D. E., Keljo, D. & 17 others, Cohen, S., Oliva-Hemker, M., Heyman, M. B., Otley, A., Baker, S. S., Evans, J. S., Kirschner, B. S., Patel, A. S., Ziring, D., Stephens, M. C., Baldassano, R., Dubinsky, M. C., Markowitz, J., Denson, L. A., Hyams, J., Kugathasan, S. & Ananthakrishnan, A. N., Oct 1 2018, In : American Journal of Gastroenterology. 113, 10, p. 1524-1529 6 p.

Research output: Contribution to journalArticle

Environmental Exposure
Crohn Disease
Phenotype
Hospitalization
Breast Feeding
2017
10 Citations (Scopus)

Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

Hyams, J. S., Davis, S., Mack, D. R., Boyle, B., Griffiths, A. M., LeLeiko, N. S., Sauer, C. G., Keljo, D. J., Markowitz, J., Baker, S. S., Rosh, J., Baldassano, R. N., Patel, A., Pfefferkorn, M., Otley, A., Heyman, M., Noe, J., Oliva-Hemker, M., Rufo, P., Strople, J. & 23 others, Ziring, D., Guthery, S. L., Sudel, B., Benkov, K., Wali, P., Moulton, D., Evans, J., Kappelman, M. D., Marquis, A., Sylvester, F. A., Collins, M. H., Venkateswaran, S., Dubinsky, M., Tangpricha, V., Spada, K. L., Britt, A., Saul, B., Gotman, N., Wang, J., Serrano, J., Kugathasan, S., Walters, T. & Denson, L. A., Dec 1 2017, In : The Lancet Gastroenterology and Hepatology. 2, 12, p. 855-868 14 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Adrenal Cortex Hormones
Cohort Studies
Mesalamine
Therapeutics
8 Citations (Scopus)

Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed with Ulcerative Colitis

Boyle, B., Collins, M. H., Wang, Z., MacK, D., Griffiths, A., Sauer, C., Markowitz, J., Leleiko, N., Keljo, D., Rosh, J., Baker, S. S., Pfefferkorn, M., Heyman, M., Patel, A., Baldassano, R., Noe, J., Rufo, P., Kugathasan, S., Walters, T., Denson, L. & 1 others, Hyams, J., Jan 1 2017, In : American Journal of Surgical Pathology. 41, 11, p. 1491-1498 8 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Inflammation
Eosinophils
Abscess
Endoscopy
14 Citations (Scopus)

Long-Term Efficacy and Safety of Adalimumab in Pediatric Patients with Crohn's Disease

Faubion, W. A., Dubinsky, M., Ruemmele, F. M., Escher, J., Rosh, J., Hyams, J. S., Eichner, S., Li, Y., Reilly, N., Thakkar, R. B., Robinson, A. M. & Lazar, A., Mar 1 2017, In : Inflammatory bowel diseases. 23, 3, p. 453-460 8 p.

Research output: Contribution to journalArticle

Crohn Disease
Pediatrics
Safety
Immunologic Factors
Adrenal Cortex Hormones
9 Citations (Scopus)

Low Vitamin D levels are associated with need for surgical correction of pediatric fractures

Minkowitz, B., Cerame, B., Poletick, E., Nguyen, J. T., Formoso, N. D., Luxenberg, S. L., Lee, B. H. & Lane, J. M., Jan 1 2017, In : Journal of Pediatric Orthopaedics. 37, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

Abbreviated Injury Scale
Vitamin D
Pediatrics
Health Surveys
Medical Records
20 Citations (Scopus)

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients

Rosen, M. J., Karns, R., Vallance, J. E., Bezold, R., Waddell, A., Collins, M. H., Haberman, Y., Minar, P., Baldassano, R. N., Hyams, J. S., Baker, S. S., Kellermayer, R., Noe, J. D., Griffiths, A. M., Rosh, J., Crandall, W. V., Heyman, M. B., Mack, D. R., Kappelman, M. D., Markowitz, J. & 7 others, Moulton, D. E., Leleiko, N. S., Walters, T. D., Kugathasan, S., Wilson, K. T., Hogan, S. P. & Denson, L. A., May 1 2017, In : Gastroenterology. 152, 6, p. 1345-1357.e7

Research output: Contribution to journalArticle

Ulcerative Colitis
Crohn Disease
Colon
Pediatrics
Genes
3 Citations (Scopus)

Pediatric Inflammatory Bowel Disease

Conrad, M. A. & Rosh, J., Jun 1 2017, In : Pediatric Clinics of North America. 64, 3, p. 577-591 15 p.

Research output: Contribution to journalReview article

Inflammatory Bowel Diseases
Gastrointestinal Tract
Pediatrics
Digestive System Endoscopy
Colonoscopy
110 Citations (Scopus)

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

Kugathasan, S., Denson, L. A., Walters, T. D., Kim, M. O., Marigorta, U. M., Schirmer, M., Mondal, K., Liu, C., Griffiths, A., Noe, J. D., Crandall, W. V., Snapper, S., Rabizadeh, S., Rosh, J., Shapiro, J. M., Guthery, S., Mack, D. R., Kellermayer, R., Kappelman, M. D., Steiner, S. & 23 others, Moulton, D. E., Keljo, D., Cohen, S., Oliva-Hemker, M., Heyman, M. B., Otley, A. R., Baker, S. S., Evans, J. S., Kirschner, B. S., Patel, A. S., Ziring, D., Trapnell, B. C., Sylvester, F. A., Stephens, M. C., Baldassano, R. N., Markowitz, J. F., Cho, J., Xavier, R. J., Huttenhower, C., Aronow, B. J., Gibson, G., Hyams, J. S. & Dubinsky, M. C., Apr 29 2017, In : The Lancet. 389, 10080, p. 1710-1718 9 p.

Research output: Contribution to journalArticle

Crohn Disease
Cohort Studies
Tumor Necrosis Factor-alpha
Serology
Ruminococcus
7 Citations (Scopus)

Subcutaneous Golimumab in Pediatric Ulcerative Colitis: Pharmacokinetics and Clinical Benefit

Hyams, J. S., Chan, D., Adedokun, O. J., Padgett, L., Turner, D., Griffiths, A., Veereman, G., Heyman, M. B., Rosh, J., Wahbeh, G. & Strauss, R., Dec 1 2017, In : Inflammatory bowel diseases. 23, 12, p. 2227-2237 11 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Ulcerative Colitis
Pediatrics
Weights and Measures
Tumor Necrosis Factor-alpha
4 Citations (Scopus)

The Crohn's and Colitis Foundation of America Survey of Inflammatory Bowel Disease Patient Health Care Access

Rubin, D. T., Feld, L. D., Goeppinger, S. R., Margolese, J., Rosh, J., Rubin, M., Kim, S., Rodriquez, D. M. & Wingate, L., Feb 1 2017, In : Inflammatory bowel diseases. 23, 2, p. 224-232 9 p.

Research output: Contribution to journalArticle

Colitis
Inflammatory Bowel Diseases
Patient Care
Delivery of Health Care
Insurance Coverage
2016
13 Citations (Scopus)

Efficacy and safety of escalation of adalimumab therapy to weekly dosing in pediatric patients with Crohn's disease

Dubinsky, M. C., Rosh, J., Faubion, W. A., Kierkus, J., Ruemmele, F., Hyams, J. S., Eichner, S., Li, Y., Huang, B., Mostafa, N. M., Lazar, A. & Thakkar, R. B., Mar 9 2016, In : Inflammatory bowel diseases. 22, 4, p. 886-893 8 p.

Research output: Contribution to journalArticle

Crohn Disease
Pediatrics
Safety
Therapeutics
Adalimumab

Preface. Clinical GI Challenges in the Adolescent

Rosh, J., Heitlinger, L. A. & Rosenfeld, W. D., Mar 1 2016, In : Adolescent medicine: state of the art reviews. 27, 1, p. xiii

Research output: Contribution to journalEditorial

Diet Fads
Eosinophilic Esophagitis
Adolescent Medicine
Vitamin D Deficiency
Celiac Disease
2015
5 Citations (Scopus)

A 4-year, open-label, multicenter, randomized trial of genotropin® growth hormone in patients with idiopathic short stature: Analysis of 4-year data comparing efficacy, efficiency, and safety between an individualized, target-driven regimen and standard dosing

Counts, D. R., Silverman, L., Rajicic, N., Geffner, M. E., Newfield, R. S., Thornton, P., Carakushansky, M., Escobar, O., Rapaport, R., Levitsky, L., Rotenstein, D., Hey-Hadavi, J. & Wajnrajch, M. P., Aug 27 2015, In : Hormone Research in Paediatrics. 84, 2, p. 79-87 9 p.

Research output: Contribution to journalArticle

Human Growth Hormone
Growth Hormone
Multicenter Studies
Safety
Weights and Measures
22 Citations (Scopus)

Dissecting allele architecture of early onset IBD using high-density genotyping

Rabizadeh, S., Noe, J., Snapper, S., Otley, A., Cohen, S., Oliva-Hemker, M., Kirschner, B., Ashish, P., Ziring, D., Evans, J., Baker, S., Cutler, D. J., Zwick, M. E., Okou, D. T., Prahalad, S., Walters, T., Guthery, S. L., Dubinsky, M., Baldassano, R., Crandall, W. V. & 25 others, Rosh, J., Markowitz, J., Stephens, M., Kellermayer, R., Pfefferkorn, M., Heyman, M. B., LeLeiko, N., Mack, D., Moulton, D., Kappelman, M. D., Kumar, A., Prince, J., Bose, P., Mondal, K., Ramachandran, D., Bohnsack, J. F., Griffiths, A. M., Haberman, Y., Essers, J., Thompson, S. D., Aronow, B., Keljo, D. J., Hyams, J. S., Denson, L. A. & Kugathasan, S., Jun 22 2015, In : PLoS ONE. 10, 6, e0128074.

Research output: Contribution to journalArticle

inflammatory bowel disease
Inflammatory Bowel Diseases
genotyping
Alleles
alleles
23 Citations (Scopus)

Efficacy of oral methotrexate in paediatric Crohn's disease: A multicentre propensity score study

Turner, D., Doveh, E., Cohen, A., Wilson, M. L., Grossman, A. B., Rosh, J., Lu, Y., Bousvaros, A., Deslandres, C., Noble, A., Baldassano, R. N., Levine, A., Lerner, A., Wilson, D. C. & Griffiths, A. M., Dec 1 2015, In : Gut. 64, 12, p. 1898-1904 7 p.

Research output: Contribution to journalArticle

Propensity Score
Methotrexate
Crohn Disease
Nausea
Oral Administration
7 Citations (Scopus)

Erratum: Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature (Journal of Clinical Investigation (2014) 124: 8 (3617-3633) DOI: 10.1172/JCI75436)

Haberman, Y., Tickle, T. L., Dexheimer, P. J., Kim, M. O., Tang, D., Karns, R., Baldassano, R. N., Noe, J. D., Rosh, J., Markowitz, J., Heyman, M. B., Griffiths, A. M., Crandall, W. V., Mack, D. R., Baker, S. S., Huttenhower, C., Keljo, D. J., Hyams, J. S., Kugathasan, S., Walters, T. D. & 4 others, Aronow, B., Xavier, R. J., Gevers, D. & Denson, L. A., Jan 1 2015, In : Journal of Clinical Investigation. 125, 3, 1 p.

Research output: Contribution to journalComment/debate

Microbiota
Transcriptome
Pediatric Crohn's disease
12 Citations (Scopus)

Evaluation of the american-english quality of life in short stature youth (QoLISSY) questionnaire in the United States

Bullinger, M., Sommer, R., Pleil, A., Mauras, N., Ross, J., Newfield, R., Silverman, L., Rohenkohl, A., Fox, J. & Quitmann, J., Apr 2 2015, In : Health and Quality of Life Outcomes. 13, 1, 43.

Research output: Contribution to journalArticle

Quality of Life
Surveys and Questionnaires
Health Services Research
Focus Groups
Psychometrics
37 Citations (Scopus)

Pharmacokinetics and exposure-efficacy relationship of adalimumab in pediatric patients with moderate to severe Crohn's disease: Results from a randomized, multicenter, phase-3 study

Sharma, S., Eckert, D., Hyams, J. S., Mensing, S., Thakkar, R. B., Robinson, A. M., Rosh, J., Ruemmele, F. M. & Awni, W. M., Mar 6 2015, In : Inflammatory bowel diseases. 21, 4, p. 783-792 10 p.

Research output: Contribution to journalArticle

Crohn Disease
Pharmacokinetics
Pediatrics
Serum
Adalimumab
9 Citations (Scopus)

Sports Participation in Children and Adolescents with Immune Thrombocytopenia (ITP)

Kumar, M., Lambert, M. P., Breakey, V., Buchanan, G. R., Neier, M., Neufeld, E. J., Kempert, P., Neunert, C. E., Nottage, K. & Klaassen, R. J., Dec 1 2015, In : Pediatric Blood and Cancer. 62, 12, p. 2223-2225 3 p.

Research output: Contribution to journalArticle

Idiopathic Thrombocytopenic Purpura
Sports
Physicians
Platelet Count
Quality of Life
2014
112 Citations (Scopus)

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease

Walters, T. D., Kim, M. O., Denson, L. A., Griffiths, A. M., Dubinsky, M., Markowitz, J., Baldassano, R., Crandall, W., Rosh, J., Pfefferkorn, M., Otley, A., Heyman, M. B., Leleiko, N., Baker, S., Guthery, S. L., Evans, J., Ziring, D., Kellermayer, R., Stephens, M., Mack, D. & 10 others, Oliva-Hemker, M., Patel, A. S., Kirschner, B., Moulton, D., Cohen, S., Kim, S., Liu, C., Essers, J., Kugathasan, S. & Hyams, J. S., Jan 1 2014, In : Gastroenterology. 146, 2, p. 383-391 9 p.

Research output: Contribution to journalArticle

Immunologic Factors
Secondary Prevention
Crohn Disease
Tumor Necrosis Factor-alpha
Therapeutics
180 Citations (Scopus)

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

Haberman, Y., Tickle, T. L., Dexheimer, P. J., Kim, M. O., Tang, D., Karns, R., Baldassano, R. N., Noe, J. D., Rosh, J., Markowitz, J., Heyman, M. B., Griffiths, A. M., Crandall, W. V., Mack, D. R., Baker, S. S., Huttenhower, C., Keljo, D. J., Hyams, J. S., Kugathasan, S., Walters, T. D. & 4 others, Aronow, B., Xavier, R. J., Gevers, D. & Denson, L. A., Aug 1 2014, In : Journal of Clinical Investigation. 124, 8, p. 3617-3633 17 p.

Research output: Contribution to journalArticle

Microbiota
Transcriptome
Crohn Disease
Ulcerative Colitis
Ileum
19 Citations (Scopus)

Review of outcomes after cessation of gonadotropin-releasing hormone agonist treatment of girls with precocious puberty

Thornton, P., Silverman, L., Geffner, M. E., Neely, E. K., Gould, E. & Danoff, T. M., Mar 1 2014, In : Pediatric Endocrinology Reviews. 11, 3, p. 306-317 12 p.

Research output: Contribution to journalArticle

Precocious Puberty
Gonadotropin-Releasing Hormone
Therapeutics
Polycystic Ovary Syndrome
Reproductive Health
12 Citations (Scopus)

Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease

Minar, P., Haberman, Y., Jurickova, I., Wen, T., Rothenberg, M. E., Kim, M. O., Saeed, S. A., Baldassano, R. N., Stephens, M., Markowitz, J., Rosh, J., Crandall, W. V., Heyman, M. B., Mack, D. R., Griffiths, A. M., Baker, S. S., Hyams, J. S., Kugathasan, S. & Denson, L. A., Jan 1 2014, In : Inflammatory bowel diseases. 20, 6, p. 1037-1048 12 p.

Research output: Contribution to journalArticle

Fc Receptors
Crohn Disease
Neutrophils
Biomarkers
Inflammation
2013
5 Citations (Scopus)
Human Growth Hormone
Growth Hormone
Therapeutics
Growth
Reference Values

Functional dyspepsia

Leiby, A. & Chitkara, D. K., Jan 1 2013, Pediatric Neurogastroenterology: Gastrointestinal Motility and Functional Disorders in Children. Humana Press Inc., p. 359-366 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dyspepsia
2012
24 Citations (Scopus)

Chronic transfusion practices for prevention of primary stroke in children with sickle cell anemia and abnormal TCD velocities

Aygun, B., Wruck, L. M., Schultz, W. H., Mueller, B. U., Brown, C., Luchtman-Jones, L., Jackson, S., Iyer, R., Rogers, Z. R., Sarnaik, S., Thompson, A. A., Gauger, C., Helms, R. W., Ware, R. E., Mueller, B., Dinu, B., Viswanathan, K., Sommerville-Brooks, N., Brown, C., Record, B. & 49 others, Heeney, M., Anderson, M., Kwiatkowski, J. L., Olson, J., Brown, M., Krishnamurti, L., McCollum, R., Godder, K., Newlin, J., Owen, W., Nelson, S., Thompson, A. A., Bianchi, K., Luchtman-Jones, L., Brown, S., Lee, M., Thornburg, C., Daeschner, C., Brown, C., Jackson, S., Kuisel, L., Nagasubramanian, R., Gauger, C., Berman, B., DeBarr, M., Singh, S., Farrell, A., Aygun, B., Hansbury, E., Miller, S., Rey, K., Odame, I., Parmar, N., Merelles-Pulcinni, M., Rogers, Z. R., Adix, L., Hilliard, L., Dumas, J., Neier, M., Farias, S., Ofelia Alvarez, A., Patrice Williams, W., Iyer, R., Walker, M. T., Imran, H., Durggin, S., Yang, E., Sarnaik, S. & Murphy, M., Apr 1 2012, In : American Journal of Hematology. 87, 4, p. 428-430 3 p.

Research output: Contribution to journalLetter

26 Citations (Scopus)

Management of melanomas in children and young adults

Neier, M., Pappo, A. & Navid, F., May 1 2012, In : Journal of Pediatric Hematology/Oncology. 34, SUPPL. 2

Research output: Contribution to journalReview article

Young Adult
Melanoma
Population
Epidemiology
Guidelines
17 Citations (Scopus)

Response to steroids predicts response to rituximab in pediatric chronic immune thrombocytopenia

Grace, R. F., Bennett, C. M., Ritchey, A. K., Jeng, M., Thornburg, C. D., Lambert, M. P., Neier, M., Recht, M., Kumar, M., Blanchette, V., Klaassen, R. J., Buchanan, G. R., Kurth, M. H., Nugent, D. J., Thompson, A. A., Stine, K., Kalish, L. A. & Neufeld, E. J., Feb 1 2012, In : Pediatric Blood and Cancer. 58, 2, p. 221-225 5 p.

Research output: Contribution to journalArticle

Idiopathic Thrombocytopenic Purpura
Steroids
Pediatrics
Platelet Count
Therapeutics