Research Output 1979 2018

Filter
Article
2018
6 Citations (Scopus)

Phase 1/2 trial of temsirolimus and sorafenib in the treatment of patients with recurrent glioblastoma: North Central Cancer Treatment Group Study/Alliance N0572

Schiff, D., Jaeckle, K., Anderson, S. K., Galanis, E., Giannini, C., Buckner, J. C., Stella, P., Flynn, P. J., Erickson, B. J., Schwerkoske, J. F., Kaluza, V., Twohy, E., Dancey, J., Wright, J. & Sarkaria, J. N., Apr 1 2018, In : Cancer. 124, 7, p. 1455-1463 9 p.

Research output: Contribution to journalArticle

Glioblastoma
Vascular Endothelial Growth Factor A
Neoplasms
Maximum Tolerated Dose
temozolomide
6 Citations (Scopus)

Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: Results of Alliance N0874/ABTC 02

Galanis, E., Keith Anderson, S., Miller, C. R., Sarkaria, J. N., Jaeckle, K., Buckner, J. C., Ligon, K. L., Ballman, K. V., Moore, D. F., Nebozhyn, M., Loboda, A., Schiff, D., Ahluwalia, M. S., Lee, E. Q., Gerstner, E. R., Lesser, G. J., Prados, M., Grossman, S. A., Cerhan, J., Giannini, C. & 1 others, Wen, P. Y., Mar 27 2018, In : Neuro-Oncology. 20, 4, p. 546-556 11 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Radiotherapy
Neutropenia
Disease-Free Survival
1 Citation (Scopus)

Treatment of a glioblastoma multiforme dural metastasis with stereotactic radiosurgery: A case report and select review of the literature

Hintenlang, L. L., Miller, D. H., Kaleem, T., Patel, N., May, B. C., Tzou, K. S., Vallow, L. A., Buskirk, S. J., Miller, R. C., Ko, S. J., Jaeckle, K., Trifiletti, D. M. & Peterson, J. L., Feb 1 2018, In : Journal of Clinical Neuroscience. 48, p. 118-121 4 p.

Research output: Contribution to journalArticle

Radiosurgery
Glioblastoma
Neoplasm Metastasis
temozolomide
Therapeutics
2017
24 Citations (Scopus)

Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: Results of nrg oncology RTOG 9813

Chang, S., Zhang, P., Cairncross, J. G., Gilbert, M. R., Bahary, J. P., Dolinskas, C. A., Chakravarti, A., Aldape, K. D., Bell, E. H., Schiff, D., Jaeckle, K., Brown, P. D., Barger, G. R., Werner-Wasik, M., Shih, H., Brachman, D., Penas-Prado, M., Robins, H. I., Belanger, K., Schultz, C. & 2 others, Hunter, G. & Mehta, M., Jan 1 2017, In : Neuro-Oncology. 19, 2, p. 252-258 7 p.

Research output: Contribution to journalArticle

temozolomide
Astrocytoma
Radiotherapy
Radiation
Survival
14 Citations (Scopus)

Stereotactic Radiosurgery With or Without Whole-Brain Radiation Therapy for Limited Brain Metastases: A Secondary Analysis of the North Central Cancer Treatment Group N0574 (Alliance) Randomized Controlled Trial

Churilla, T. M., Ballman, K. V., Brown, P. D., Twohy, E. L., Jaeckle, K., Farace, E., Cerhan, J. H., Anderson, S. K., Carrero, X. W., Garces, Y. I., Barker, F. G., Deming, R., Dixon, J. G., Burri, S. H., Chung, C., Ménard, C., Stieber, V. W., Pollock, B. E., Galanis, E., Buckner, J. C. & 1 others, Asher, A. L., Dec 1 2017, In : International Journal of Radiation Oncology Biology Physics. 99, 5, p. 1173-1178 6 p.

Research output: Contribution to journalArticle

Radiosurgery
metastasis
brain
radiation therapy
Radiotherapy
22 Citations (Scopus)

The Neurologic Assessment in Neuro-Oncology (NANO) scale: A tool to assess neurologic function for integration into the Response Assessment in Neuro-Oncology (RANO) criteria

Nayak, L., Deangelis, L. M., Brandes, A. A., Peereboom, D. M., Galanis, E., Lin, N. U., Soffietti, R., MacDonald, D. R., Chamberlain, M., Perry, J., Jaeckle, K., Mehta, M., Stupp, R., Muzikansky, A., Pentsova, E., Cloughesy, T., Iwamoto, F. M., Tonn, J. C., Vogelbaum, M. A., Wen, P. Y. & 2 others, Van Den Bent, M. J. & Reardon, D. A., May 1 2017, In : Neuro-Oncology. 19, 5, p. 625-635 11 p.

Research output: Contribution to journalArticle

Nervous System
Outcome Assessment (Health Care)
Observer Variation
Brain Neoplasms
Glioma
2016
353 Citations (Scopus)

Effect of radiosurgery alone vs radiosurgery with whole brain radiation therapy on cognitive function in patients with 1 to 3 brain metastases a randomized clinical trial

Brown, P. D., Jaeckle, K., Ballman, K. V., Farace, E., Cerhan, J. H., Keith Anderson, S., Carrero, X. W., Barker, F. G., Deming, R., Burri, S. H., Ménard, C., Chung, C., Stieber, V. W., Pollock, B. E., Galanis, E., Buckner, J. C. & Asher, A. L., Jul 26 2016, In : JAMA - Journal of the American Medical Association. 316, 4, p. 401-409 9 p.

Research output: Contribution to journalArticle

Radiosurgery
Cognition
Radiotherapy
Randomized Controlled Trials
Neoplasm Metastasis
2015
49 Citations (Scopus)

A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K

Ma, D. J., Galanis, E., Anderson, S. K., Schiff, D., Kaufmann, T. J., Peller, P. J., Giannini, C., Brown, P. D., Uhm, J. H., McGraw, S., Jaeckle, K., Flynn, P. J., Ligon, K. L., Buckner, J. C. & Sarkaria, J. N., Sep 1 2015, In : Neuro-Oncology. 17, 9, p. 1261-1269 9 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Radiotherapy
Sirolimus
Phosphatidylinositol 3-Kinase
7 Citations (Scopus)

Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure

Berg, A. K., Buckner, J. C., Galanis, E., Jaeckle, K., Ames, M. M. & Reid, J. M., Nov 1 2015, In : Journal of Clinical Pharmacology. 55, 11, p. 1303-1312 10 p.

Research output: Contribution to journalArticle

irinotecan
Anticonvulsants
Pharmacokinetics
Enzymes
Glioma
2014
1139 Citations (Scopus)

A randomized trial of bevacizumab for newly diagnosed glioblastoma

Gilbert, M. R., Dignam, J. J., Armstrong, T. S., Wefel, J. S., Blumenthal, D. T., Vogelbaum, M. A., Colman, H., Chakravarti, A., Pugh, S., Won, M., Jeraj, R., Brown, P. D., Jaeckle, K. A., Schiff, D., Stieber, V. W., Brachman, D. G., Werner-Wasik, M., Tremont-Lukats, I. W., Sulman, E. P., Aldape, K. D. & 2 others, Curran, W. J. & Mehta, M. P., Jan 1 2014, In : New England Journal of Medicine. 370, 8, p. 699-708 10 p.

Research output: Contribution to journalArticle

Glioblastoma
temozolomide
Radiotherapy
Placebos
Risk Reduction Behavior
8 Citations (Scopus)

Oligodendroglial tumors

Jaeckle, K., Jan 1 2014, In : Seminars in Oncology. 41, 4, p. 468-477 10 p.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
Radiation Oncology
Neuroglia
Radiotherapy
2013
396 Citations (Scopus)

Dose-dense temozolomide for newly diagnosed glioblastoma: A randomized phase III clinical trial

Gilbert, M. R., Wang, M., Aldape, K. D., Stupp, R., Hegi, M. E., Jaeckle, K., Armstrong, T. S., Wefel, J. S., Won, M., Blumenthal, D. T., Mahajan, A., Schultz, C. J., Erridge, S., Baumert, B., Hopkins, K. I., Tzuk-Shina, T., Brown, P. D., Chakravarti, A., Curran, W. J. & Mehta, M. P., Nov 10 2013, In : Journal of Clinical Oncology. 31, 32, p. 4085-4091 7 p.

Research output: Contribution to journalArticle

temozolomide
Phase III Clinical Trials
Methyltransferases
Glioblastoma
Randomized Controlled Trials
74 Citations (Scopus)

Phase II study of bevacizumab in combination with sorafenib in recurrent glioblastoma (N0776): A North Central Cancer Treatment Group Trial

Galanis, E., Anderson, S. K., Lafky, J. M., Uhm, J. H., Giannini, C., Kumar, S. K., Kimlinger, T. K., Northfelt, D. W., Flynn, P. J., Jaeckle, K., Kaufmann, T. J. & Buckner, J. C., Sep 1 2013, In : Clinical Cancer Research. 19, 17, p. 4816-4823 8 p.

Research output: Contribution to journalArticle

Glioblastoma
Vascular Endothelial Growth Factor A
Neoplasms
Single Nucleotide Polymorphism
Biomarkers
2012
116 Citations (Scopus)

Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: A north central cancer treatment group study

Friday, B. B., Anderson, S. K., Buckner, J., Yu, C., Giannini, C., Geoffroy, F., Schwerkoske, J., Mazurczak, M., Gross, H., Pajon, E., Jaeckle, K. & Galanis, E., Feb 1 2012, In : Neuro-Oncology. 14, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

Glioblastoma
Neoplasms
Proteasome Inhibitors
Histone Deacetylase Inhibitors
Therapeutics
7 Citations (Scopus)

Primary central nervous system B cell lymphoma with features intermediate between diffuse large B cell lymphoma and burkitt lymphoma

Jiang, L., Li, Z., Finn, L. E., Personnet, D. A., Edenfield, B., Foran, J. M., Jaeckle, K., Reimer, R., Menke, D. M., Ketterling, R. P. & Tun, H. W., Feb 13 2012, In : International Journal of Clinical and Experimental Pathology. 5, 1, p. 72-76 5 p.

Research output: Contribution to journalArticle

Burkitt Lymphoma
Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Central Nervous System
Lymphoma
2011
55 Citations (Scopus)

North central cancer treatment group Phase i trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme

Sarkaria, J. N., Galanis, E., Wu, W., Peller, P. J., Giannini, C., Brown, P. D., Uhm, J. H., McGraw, S., Jaeckle, K. & Buckner, J. C., Oct 1 2011, In : International Journal of Radiation Oncology Biology Physics. 81, 2, p. 468-475 8 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
radiation therapy
Radiotherapy
cancer
84 Citations (Scopus)

Phase II evaluation of gefitinib in patients with newly diagnosed grade 4 astrocytoma: Mayo/north central cancer treatment group study n0074

Uhm, J. H., Ballman, K. V., Wu, W., Giannini, C., Krauss, J. C., Buckner, J. C., James, C. D., Scheithauer, B. W., Behrens, R. J., Flynn, P. J., Schaefer, P. L., Dakhill, S. R. & Jaeckle, K. A., Jun 1 2011, In : International Journal of Radiation Oncology Biology Physics. 80, 2, p. 347-353 7 p.

Research output: Contribution to journalArticle

Astrocytoma
Glioblastoma
grade
cancer
evaluation
2010
54 Citations (Scopus)

Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks

Sarkaria, J. N., Galanis, E., Wu, W., Dietz, A. B., Kaufmann, T. J., Gustafson, M. P., Brown, P. D., Uhm, J. H., Rao, R. D., Doyle, L., Giannini, C., Jaeckle, K. A. & Buckner, J. C., Nov 15 2010, In : Clinical Cancer Research. 16, 22, p. 5573-5580 8 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Radiation
Antibiotic Prophylaxis
Chemoradiotherapy
50 Citations (Scopus)

Joint NCCTG and NABTC prognostic factors analysis for high-grade recurrent glioma

Wu, W., Lamborn, K. R., Buckner, J. C., Novotny, P. J., Chang, S. M., O'Fallon, J. R., Jaeckle, K. A. & Prados, M. D., Feb 1 2010, In : Neuro-Oncology. 12, 2, p. 164-172 9 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Glioma
Statistical Factor Analysis
Joints
Disease-Free Survival
5 Citations (Scopus)

Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM

Jaeckle, K., Ballman, K. V., Giannini, C., Schomberg, P. J., Ames, M. M., Reid, J. M., McGovern, R. M., Safgren, S. L., Galanis, E., Uhm, J. H., Brown, P. D., Hammack, J. E., Arusell, R., Nikcevich, D. A., Morton, R. F., Wender, D. B. & Buckner, J. C., Aug 1 2010, In : Journal of Neuro-Oncology. 99, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

irinotecan
Carmustine
Anticonvulsants
Alleles
Area Under Curve
2009
74 Citations (Scopus)

Correlation of enzyme-inducing anticonvulsant use with outcome of patients with glioblastoma

Jaeckle, K. A., Ballman, K., Furth, A. & Buckner, J. C., Oct 2009, In : Neurology. 73, 15, p. 1207-1213 7 p.

Research output: Contribution to journalArticle

Glioblastoma
Anticonvulsants
Enzymes
Disease-Free Survival
Cytochrome P-450 Enzyme System
24 Citations (Scopus)

Phase II trial of two different irinotecan schedules with pharmacokinetic analysis in patients with recurrent glioma: North Central Cancer Treatment Group results

Santisteban, M., Buckner, J. C., Reid, J. M., Wu, W., Scheithauer, B. W., Ames, M. M., Felten, S. J., Nikcevich, D. A., Wiesenfeld, M., Jaeckle, K. & Galanis, E., Jan 1 2009, In : Journal of Neuro-Oncology. 92, 2, p. 165-175 11 p.

Research output: Contribution to journalArticle

irinotecan
Glioma
Appointments and Schedules
Pharmacokinetics
Neoplasms
222 Citations (Scopus)

Phase II trial of Vorinostat in recurrent glioblastoma multiforme: A north central cancer treatment group study

Galanis, E., Jaeckle, K., Maurer, M. J., Reid, J. M., Ames, M. M., Hardwick, J. S., Reilly, J. F., Loboda, A., Nebozhyn, M., Fantin, V. R., Richon, V. M., Scheithauer, B., Giannini, C., Flynn, P. J., Moore, D. F., Zwiebel, J. & Buckner, J. C., Apr 20 2009, In : Journal of Clinical Oncology. 27, 12, p. 2052-2058 7 p.

Research output: Contribution to journalArticle

Glioblastoma
Neoplasms
Therapeutics
Histones
Acetylation
2008
3 Citations (Scopus)

North Central Cancer Treatment Group-Achievements and Perspectives

Grothey, A., Adjei, A. A., Alberts, S. R., Perez, E. A., Jaeckle, K., Loprinzi, C. L., Sargent, D. J., Sloan, J. A. & Buckner, J. C., Oct 1 2008, In : Seminars in Oncology. 35, 5, p. 530-544 15 p.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
Quality of Life
Clinical Trials
Research
114 Citations (Scopus)

Pathway analysis of primary central nervous system lymphoma

Tun, H. W., Personett, D., Baskerville, K. A., Menke, D. M., Jaeckle, K. A., Kreinest, P., Edenfield, B., Zubair, A. C., O'Neill, B. P., Lai, W. R., Park, P. J. & McKinney, M., Mar 15 2008, In : Blood. 111, 6, p. 3200-3210 11 p.

Research output: Contribution to journalArticle

Neurology
Lymphoma
Central Nervous System
Extracellular Matrix
Gene expression
185 Citations (Scopus)

Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North central cancer treatment group study N0177

Brown, P. D., Krishnan, S., Sarkaria, J. N., Wu, W., Jaeckle, K., Uhm, J. H., Geoffroy, F. J., Arusell, R., Kitange, G., Jenkins, R. B., Kugler, J. W., Morton, R. F., Rowland, K. M., Mischel, P., Yong, W. H., Scheithauer, B. W., Schiff, D., Giannini, C. & Buckner, J. C., Dec 1 2008, In : Journal of Clinical Oncology. 26, 34, p. 5603-5609 7 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Radiotherapy
Epidermal Growth Factor Receptor
Neoplasms
2007
221 Citations (Scopus)

The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme

Ballman, K. V., Buckner, J. C., Brown, P. D., Giannini, C., Flynn, P. J., LaPlant, B. R. & Jaeckle, K. A., Jan 1 2007, In : Neuro-Oncology. 9, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

Glioblastoma
Disease-Free Survival
Survival
Radiotherapy
Proportional Hazards Models
2006
153 Citations (Scopus)

A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: A North American Brain Tumor Consortium study

Prados, M. D., Lamborn, K., Yung, W. K. A., Jaeckle, K., Robins, H. I., Mehta, M., Fine, H. A., Wen, P. Y., Cloughesy, T., Chang, S., Nicholas, M. K., Schiff, D., Greenberg, H., Junck, L., Fink, K., Hess, K. & Kuhn, J., Apr 1 2006, In : Neuro-Oncology. 8, 2, p. 189-193 5 p.

Research output: Contribution to journalArticle

irinotecan
Brain Neoplasms
Glioma
Glioblastoma
Anticonvulsants
62 Citations (Scopus)

Detrimental effects of tumor progression on cognitive function of patients with high-grade glioma

Brown, P. D., Jensen, A. W., Felten, S. J., Ballman, K. V., Schaefer, P. L., Jaeckle, K. A., Cerhan, J. H. & Buckner, J. C., Dec 1 2006, In : Journal of Clinical Oncology. 24, 34, p. 5427-5433 7 p.

Research output: Contribution to journalArticle

Glioma
Cognition
Neoplasms
Brain Neoplasms
Radiation
54 Citations (Scopus)

Neoplastic Meningitis From Systemic Malignancies: Diagnosis, Prognosis and Treatment

Jaeckle, K., Jun 1 2006, In : Seminars in Oncology. 33, 3, p. 312-323 12 p.

Research output: Contribution to journalArticle

Meningitis
Survival
Neoplasms
Cerebrospinal Fluid
Breast Neoplasms
20 Citations (Scopus)

Nonconvulsive status epilepticus in metastatic CNS disease

Blitshteyn, S. & Jaeckle, K., Apr 1 2006, In : Neurology. 66, 8, p. 1261-1263 3 p.

Research output: Contribution to journalArticle

Status Epilepticus
Central Nervous System Diseases
Anticonvulsants
Differential Diagnosis
Therapeutics
17 Citations (Scopus)

Ototoxicity of cisplatin plus standard radiation therapy vs. accelerated radiation therapy in glioblastoma patients

Marshall, N. E., Ballman, K. V., Michalak, J. C., Schomberg, P. J., Burton, G. V., Sandler, H. M., Cascino, T. L., Jaeckle, K. & Buckner, J. C., May 1 2006, In : Journal of Neuro-Oncology. 77, 3, p. 315-320 6 p.

Research output: Contribution to journalArticle

Glioblastoma
Cisplatin
Carmustine
Radiotherapy
Hearing Loss
42 Citations (Scopus)

Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: A relationship among efficacy, joint toxicity and anticonvulsant status

Groves, M. D., Puduvalli, V. K., Conrad, C. A., Gilbert, M. R., Yung, W. K. A., Jaeckle, K., Liu, V., Hess, K. R., Aldape, K. D. & Levin, V. A., Oct 1 2006, In : Journal of Neuro-Oncology. 80, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

temozolomide
Glioma
Anticonvulsants
Joints
Confidence Intervals
75 Citations (Scopus)

Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: Results of North Central Cancer Treatment Group protocol N0177

Krishnan, S., Brown, P. D., Ballman, K. V., Fiveash, J. B., Uhm, J. H., Giannini, C., Jaeckle, K., Geoffroy, F. J., Nabors, L. B. & Buckner, J. C., Jul 15 2006, In : International Journal of Radiation Oncology Biology Physics. 65, 4, p. 1192-1199 8 p.

Research output: Contribution to journalArticle

Antineoplastic Protocols
Glioblastoma
radiation therapy
Radiotherapy
cancer
2005
53 Citations (Scopus)

Intrathecal mafosfamide: A preclinical pharmacology and phase I trial

Blaney, S. M., Balis, F. M., Berg, S., Arndt, C. A. S., Heideman, R., Geyer, J. R., Packer, R., Adamson, P. C., Jaeckle, K., Klenke, R., Aikin, A., Murphy, R., McCully, C. & Poplack, D. G., Dec 1 2005, In : Journal of Clinical Oncology. 23, 7, p. 1555-1563 9 p.

Research output: Contribution to journalArticle

Pharmacology
Headache
Pharmacokinetics
Clinical Trials, Phase I
Rhabdomyosarcoma
2004
66 Citations (Scopus)

Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: A North American brain tumor consortium study

Prados, M. D., Yung, W. K. A., Jaeckle, K., Robins, H. I., Mehta, M. P., Fine, H. A., Wen, P. Y., Cloughesy, T. F., Chang, S. M., Nicholas, M. K., Schiff, D., Greenberg, H. S., Junck, L., Fink, K. L., Hess, K. R. & Kuhn, J., Jan 1 2004, In : Neuro-Oncology. 6, 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

irinotecan
Brain Neoplasms
Glioma
Anticonvulsants
Area Under Curve
60 Citations (Scopus)

Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American brain tumor consortium study

Prados, M. D., Yung, W. K. A., Fine, H. A., Greenberg, H. S., Junck, L., Chang, S. M., Nicholas, M. K., Robins, H. I., Mehta, M. P., Fink, K. L., Jaeckle, K., Kuhn, J., Hess, K. R. & Schold, S. C., Jan 1 2004, In : Neuro-Oncology. 6, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

temozolomide
Carmustine
Glioblastoma
Brain Neoplasms
Disease-Free Survival
41 Citations (Scopus)

Phase II Study of Neoadjuvant 1, 3-Bis (2-Chloroethyl)-1-Nitrosourea and Temozolomide for Newly Diagnosed Anaplastic Glioma: A North American Brain Tumor Consortium Trial

Chang, S. M., Prados, M. D., Yung, W. K. A., Fine, H., Junck, L., Greenberg, H., Robins, H. I., Mehta, M., Fink, K. L., Jaeckle, K., Kuhn, J., Hess, K. & Schold, C., Apr 15 2004, In : Cancer. 100, 8, p. 1712-1716 5 p.

Research output: Contribution to journalArticle

temozolomide
Carmustine
Brain Neoplasms
Glioma
Alkyl and Aryl Transferases
2003
63 Citations (Scopus)

Anaplastic oligodendrogliomas: Prognostic factors for tumor recurrence and survival

Puduvalli, V. K., Hashmi, M., McAllister, L. D., Levin, V. A., Hess, K. R., Prados, M., Jaeckle, K., Yung, W. K. A., Buys, S. S., Bruner, J. M., Townsend, J. J., Davis, R., Sawaya, R. & Kyritsis, A. P., Dec 17 2003, In : Oncology. 65, 3, p. 259-266 8 p.

Research output: Contribution to journalArticle

Oligodendroglioma
Recurrence
Survival
Radiotherapy
Neoplasms
117 Citations (Scopus)

A randomized, double-blind, placebo-controlled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma

Prados, M. D., Schold, S. C., Fine, H. A., Jaeckle, K., Hochberg, F., Mechtler, L., Fetell, M. R., Phuphanich, S., Feun, L., Janus, T. J., Ford, K. & Graney, W., Apr 1 2003, In : Neuro-Oncology. 5, 2, p. 96-103 8 p.

Research output: Contribution to journalArticle

Carboplatin
Glioma
Placebos
Therapeutics
Neoplasms
67 Citations (Scopus)

Phase I clinical trial of intrathecal topotecan in patients with neoplastic meningitis

Blaney, S. M., Heideman, R., Berg, S., Adamson, P., Gillespie, A., Geyer, J. R., Packer, R., Matthay, K., Jaeckle, K., Cole, D., Kuttesch, N., Poplack, D. G. & Balis, F. M., Jan 1 2003, In : Journal of Clinical Oncology. 21, 1, p. 143-147 5 p.

Research output: Contribution to journalArticle

Topotecan
Clinical Trials, Phase I
Meningitis
Poisons
Maximum Tolerated Dose
129 Citations (Scopus)

Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: A North American Brain Tumor Consortium Study

Jaeckle, K. A., Hess, K. R., Yung, W. K. A., Greenberg, H., Fine, H., Schiff, D., Pollack, I. F., Kuhn, J., Fink, K., Mehta, M., Cloughesy, T., Nicholas, M. K., Chang, S. & Prados, M., Jun 15 2003, In : Journal of Clinical Oncology. 21, 12, p. 2305-2311 7 p.

Research output: Contribution to journalArticle

temozolomide
Isotretinoin
NSC 153174
Brain Neoplasms
Glioma
94 Citations (Scopus)

Phase III randomized study of postradiotherapy chemotherapy with combination α-difluoromethylornithine-PCV versus PCV for anaplastic gliomas

Levin, V. A., Hess, K. R., Choucair, A., Flynn, P. J., Jaeckle, K., Kyritsis, A. P., Yung, W. K. A., Prados, M. D., Bruner, J. M., Ictech, S., Gleason, M. J. & Kim, H. W., Mar 1 2003, In : Clinical Cancer Research. 9, 3, p. 981-990 10 p.

Research output: Contribution to journalArticle

Eflornithine
Combination Drug Therapy
Glioma
Oligodendroglioma
Survival
69 Citations (Scopus)

Quality-of-life-adjusted survival comparison of sustained-release cytosine arabinoside versus intrathecal methotrexate for treatment of solid tumor neoplastic meningitis

Cole, B. F., Glantz, M. J., Jaeckle, K. A., Chamberlain, M. C. & Mackowiak, J. I., Jun 15 2003, In : Cancer. 97, 12, p. 3053-3060 8 p.

Research output: Contribution to journalArticle

Cytarabine
Meningitis
Methotrexate
Quality of Life
Survival
2002
90 Citations (Scopus)

An open label trial of sustained-release cytarabine (DepoCyt蒂) for the intrathecal treatment of solid tumor neoplastic meningitis

Jaeckle, K., Batchelor, T., O'Day, S. J., Phuphanich, S., New, P., Lesser, G., Cohn, A., Gilbert, M., Aiken, R., Heros, D., Rogers, L., Wong, E., Fulton, D., Gutheil, J. C., Baidas, S., Kennedy, J. M., Mason, W., Moots, P., Russell, C., Swinnen, L. J. & 1 others, Howell, S. B., Jan 1 2002, In : Journal of Neuro-Oncology. 57, 3, p. 231-239 9 p., 405930.

Research output: Contribution to journalArticle

Cytarabine
Meningitis
Nervous System
Arachnoiditis
Neoplasms
5 Citations (Scopus)

CI-980 for the treatment of recurrent or progressive malignant gliomas: National Central Nervous System Consortium phase I-II evaluation of CI-980

Kunschner, L. J., Fine, H., Hess, K., Jaeckle, K., Kyritsis, A. P. & Yung, W. K. A., Nov 23 2002, In : Cancer Investigation. 20, 7-8, p. 948-954 7 p.

Research output: Contribution to journalArticle

Glioma
Central Nervous System
Cerebellar Diseases
Therapeutics
Agranulocytosis
5 Citations (Scopus)

Phase II trial of amonafide in central nervous system tumors: A Southwest Oncology Group Study

Taylor, S. A., Rankin, C., Townsend, J. J., Craig, J. B., Vance, R. B., Solank, D. L., Brown, T. D. & Jaeckle, K., Apr 6 2002, In : Investigational New Drugs. 20, 1, p. 113-115 3 p.

Research output: Contribution to journalArticle

amonafide
Central Nervous System Neoplasms
Nervous System
Appointments and Schedules
Central Nervous System
197 Citations (Scopus)

Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme

Groves, M. D., Puduvalli, V. K., Hess, K. R., Jaeckle, K., Peterson, P., Yung, W. K. A. & Levin, V. A., Mar 1 2002, In : Journal of Clinical Oncology. 20, 5, p. 1383-1388 6 p.

Research output: Contribution to journalArticle

temozolomide
Matrix Metalloproteinase Inhibitors
Glioblastoma
Disease-Free Survival
Arthralgia
22 Citations (Scopus)

Pretreatment cognitive performance predicts survival in patients with leptomeningeal disease

Sherman, A. M., Jaeckle, K. & Meyers, C. A., Sep 15 2002, In : Cancer. 95, 6, p. 1311-1316 6 p.

Research output: Contribution to journalArticle

Survival
Dementia
Cerebrospinal Fluid
Neoplasms
Demography
2001
81 Citations (Scopus)

Intrathecal treatment of neoplastic meningitis due to breast cancer with a slow-release formulation of cytarabine

Jaeckle, K. A., Phuphanich, S., Van den Bent, M. J., Aiken, R., Batchelor, T., Campbell, T., Fulton, D., Gilbert, M., Heros, D., Rogers, L., O'Day, S. J., Akerley, W., Allen, J., Baidas, S., Gertler, S. Z., Greenberg, H. S., LaFollette, S., Lesser, G., Mason, W., Recht, L. & 12 others, Wong, E., Chamberlain, M. C., Cohn, A., Glantz, M. J., Gutheil, J. C., Maria, B., Moots, P., New, P., Russell, C., Shapiro, W., Swinnen, L. & Howell, S. B., Feb 13 2001, In : British Journal of Cancer. 84, 2, p. 157-163 7 p.

Research output: Contribution to journalArticle

Cytarabine
Meningitis
Breast Neoplasms
Arachnoiditis
Nervous System